Cochrane · systematic review · CD011344
Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour
Tan, HS, Zeng, Y, Qi, Y, et al. · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
5
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 2 · 28.6%Very low 0 · 0%Low 0 · 0%Moderate 5 · 71.4%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Current version onlyAutomated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour
Population: term, pregnant women (nulliparous, or combination of nulli‐ and muliparous) requesting for labour epidural analgesia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Breakthrough pain Automated mandatory bolus vs basal infusion | RR 0.71 [0.55, 0.91] | 16 studies · 1528 participants | Moderate Downgraded: inconsistency |
Caesarean delivery during labour epidural analgesia Automated mandatory bolus vs basal infusion | RR 0.85 [0.69, 1.06] | 16 studies · 1735 participants | Moderate Downgraded: imprecision, inconsistency |
Instrumental delivery during labour epidural analgesia Automated mandatory bolus vs basal infusion | RR 0.85 [0.71, 1.01] | 17 studies · 4550 participants | Moderate Downgraded: imprecision, inconsistency |
Duration of labour analgesia in minutes Automated mandatory bolus vs basal infusion | no estimate extracted | 17 studies · 4544 participants | Moderate Downgraded: imprecision, inconsistency |
Local anaesthetic consumption per hour (mg/hr)c during labour epidural analgesia Automated mandatory bolus vs basal infusion | no estimate extracted | 16 studies · 1642 participants | Moderate Downgraded: imprecision, inconsistency |
Maternal satisfaction following fetal delivery Automated mandatory bolus vs basal infusion | no estimate extracted | 14 studies · 14 participants | Ungraded |
Apgar scores at 1‐ and 5‐minutes following fetal delivery Automated mandatory bolus vs basal infusion | no estimate extracted | 14 studies · 14 participants | Ungraded |
Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour
Population: maintenance of epidural analgesia in labour
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Breakthrough pain Automated mandatory bolus vs basal infusion | RR 0.6 [0.39, 0.92] | 10 studies · 797 participants | Moderate Downgraded: inconsistency |
Caesarean delivery Automated mandatory bolus vs basal infusion | RR 0.92 [0.7, 1.21] | 11 studies · 1079 participants | Low Downgraded: imprecision |
Instrumental delivery Automated mandatory bolus vs basal infusion | RR 0.75 [0.54, 1.06] | 11 studies · 1079 participants | Low Downgraded: imprecision |
Duration of labour in min Automated mandatory bolus vs basal infusion | no estimate extracted | 11 studies · 1079 participants | Moderate |
LA consumption per hour Automated mandatory bolus vs basal infusion | no estimate extracted | 12 studies · 1121 participants | Moderate Downgraded: inconsistency |