Cochrane · systematic review · CD008877

Anaesthetic techniques for risk of malignant tumour recurrence

Cakmakkaya, OS, Kolodzie, K, Apfel, CC, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Epidural anaesthesia in addition to general anaesthesia compared with general anaesthesia alone for patients undergoing primary tumour surgery

Population: patients undergoing primary tumour surgery
3 questions
OutcomeEffectEvidenceStatus / GRADE
Death from all causes Range of
Epidural anaesthesia in addition to general anaesthesia vs general anaesthesia alone
HR 1.03 [0.86, 1.24]3 studies · 647 participantsLow
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Tumour progression or death from all causes Range of
Epidural anaesthesia in addition to general anaesthesia vs general anaesthesia alone
HR 0.88 [0.56, 1.38]2 studies · 535 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Tumour progression Median
Epidural anaesthesia in addition to general anaesthesia vs general anaesthesia alone
HR 1.5 [1, 2.25]2 studies · 545 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness