Cochrane · systematic review · CD001893
Epidural local anaesthetics versus opioid‐based analgesic regimens for postoperative gastrointestinal paralysis, vomiting and pain after abdominal surgery
Guay, J, Nishimori, M, Kopp, S · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 16.7%Low 3 · 50%Moderate 1 · 16.7%High 1 · 16.7%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Epidural local anaesthetic compared with opioid‐based regimen for adults
Population: adults
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time required to observe first flatus Epidural local anaesthetic vs opioid‐based regimen | no estimate extracted | 22 studies · 1138 participants | High |
Time required to observe first faeces Epidural local anaesthetic vs opioid‐based regimen | no estimate extracted | 28 studies · 1559 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
VAS scores on movement at 24 hours Epidural local anaesthetic vs opioid‐based regimen | no estimate extracted | 35 studies · 2731 participants | Moderate Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Vomiting during first 24 hours Epidural local anaesthetic vs opioid‐based regimen | RR 0.84 [0.57, 1.23] | 22 studies · 1154 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Anastomotic leak Epidural local anaesthetic vs opioid‐based regimen | RR 0.74 [0.41, 1.32] | 17 studies · 848 participants | Low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |
Length of hospital stay Epidural local anaesthetic vs opioid‐based regimen | no estimate extracted | 30 studies · 2598 participants | Very low Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias |