Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

332 questions · 335 findings · 55 reviews · Headline outcomes only

No studies found 77 · 23%GRADE not reported 3 · 0.9%Very low 113 · 33.7%Low 75 · 22.4%Moderate 61 · 18.2%High 6 · 1.8%

Summary of findings table ‐ Endoscopic sphincterotomy vs sham

Proportion of participants with ≥ 1 serious adverse events at 1 year · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Endoscopic sphincterotomy changes proportion of participants with ≥ 1 serious adverse events at 1 year compared with sham treatment (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Endoscopic sphincterotomy vs sham

Quality of life · adults with biliary sphincter of Oddi dysfunction
2 findings from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

The proportion of pressure ulcers healed · people with venous leg ulcers

Subfascial endoscopic perforator vein surgery (SEPS) + compression may leads to higher proportion with ulcers healed at 24 months compared with compression alone (low certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) + compression vs compression alone

Recurrence of ulcers · people with venous leg ulcers

It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) + compression changes ulcer recurrence at 24 months compared with compression alone (very low certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery

The proportion of pressure ulcers healed · people with venous leg ulcers

It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) + saphenous… changes proportion of ulcers healed at 12 months compared with saphenous surgery (very low certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery

Recurrence of ulcers · people with venous leg ulcers

It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) + saphenous… changes ulcer recurrence at 12 months compared with saphenous surgery (very low certainty).

1 finding from 1 review

Subfascial endoscopic perforator vein surgery (SEPS) + saphenous surgery vs saphenous surgery

Adverse events · people with venous leg ulcers

It is very uncertain whether subfascial endoscopic perforator vein surgery (SEPS) + saphenous… changes adverse events compared with saphenous surgery (very low certainty).

1 finding from 1 review