Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

334 questions · 337 findings · 56 reviews

No studies found 77 · 22.8%GRADE not reported 5 · 1.5%Very low 113 · 33.5%Low 75 · 22.3%Moderate 61 · 18.1%High 6 · 1.8%

Endoscopic vs open or mini‐open carpal tunnel release

Overall improvement at more than 3 months Participants' subjective evaluation · carpal tunnel syndrome

Endoscopic showed no clear difference in overall improvement at more than 3 months Participants' subjective… compared with open or mini‐open carpal tunnel release (low certainty).

1 finding from 1 review

Endoscopic injection treatment vs antibiotics alone

Febrile UTI by 1 to 2 years: endoscopic correction + antibiotics versus antibiotics alone · primary VUR

Endoscopic injection treatment showed no clear difference in febrile UTI by 1 to 2 years: endoscopic correction + antibiotics… compared with antibiotics alone (low certainty).

1 finding from 1 review

Endoscopic injection treatment vs antibiotics alone

Total new and progressive Renal parenchymal abnormalities on DMSA scan at 1 to 2 years: endoscopic correction + antibiotics versus antibiotics alone (unit of analysis: children) · primary VUR

Endoscopic injection treatment showed no clear difference in total new and progressive Renal parenchymal abnormalities on DMSA… compared with antibiotics alone (low certainty).

1 finding from 1 review

Summary of findings table ‐ Endoscopic sphincterotomy vs endoscopic papillary balloon dilation

Proportion of participants with ≥ 1 serious adverse events at 1 year · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Endoscopic sphincterotomy changes proportion of participants with ≥ 1 serious adverse events at 1 year compared with endoscopic papillary balloon dilation (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Biliary endoscopic sphincterotomy vs dual endoscopic sphincterotomy

Proportion of participants without successful treatment at 1 year · adults with biliary sphincter of Oddi dysfunction

It is very uncertain whether summary of findings table ‐ Biliary endoscopic sphincterotomy changes proportion of participants without successful treatment at 1 year compared with dual endoscopic sphincterotomy (very low certainty).

1 finding from 1 review