Cochrane · systematic review · CD008265

Endoscopic release for carpal tunnel syndrome

Vasiliadis, HS, Georgoulas, P, Shrier, I, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library

NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
10
current version
GRADE rated
10
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 10%Low 8 · 80%Moderate 1 · 10%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Endoscopic versus open or mini‐open carpal tunnel release for carpal tunnel syndrome

Population: participants with carpal tunnel syndrome
10 questions
OutcomeEffectEvidenceStatus / GRADE
Symptom Severity Scale (Levine) at 3 months or less Participants' self assessment questionnaire. Scale from: 1 to 5.
Endoscopic vs open or mini‐open carpal tunnel release
no estimate extracted5 studies · 551 participantsLow
Downgraded: risk of bias, inconsistency
Functional Status Scale (Levine) at 3 months or less Participants' self assessment questionnaire. Scale from: 1 to 5.
Endoscopic vs open or mini‐open carpal tunnel release
no estimate extracted5 studies · 551 participantsLow
Downgraded: risk of bias, inconsistency
Grip strength at 3 months or less Dynamometer
Endoscopic vs open or mini‐open carpal tunnel release
no estimate extracted6 studies · 560 participantsModerate
Downgraded: risk of bias
Overall improvement at more than 3 months Participants' subjective evaluation
Endoscopic vs open or mini‐open carpal tunnel release
RR 1.04 [0.95, 1.14]4 studies · 317 participantsLow
Downgraded: risk of bias, imprecision
Symptom Severity Scale (Levine) at more than 3 months Participants' self assessment questionnaire. Scale from: 1 to 5.
Endoscopic vs open or mini‐open carpal tunnel release
no estimate extracted2 studies · 273 participantsLow
Downgraded: risk of bias, imprecision
Function Status Scale (Levine) at more than 3 months Participants' self assessment questionnaire. Scale from: 1 to 5.
Endoscopic vs open or mini‐open carpal tunnel release
no estimate extracted2 studies · 273 participantsLow
Downgraded: risk of bias, imprecision
Grip strength at more than 3 months Dynamometer. Scale from: 0 to 50.
Endoscopic vs open or mini‐open carpal tunnel release
no estimate extracted2 studies · 56 participantsLow
Downgraded: risk of bias, imprecision
Time to return to work (in days)
Endoscopic vs open or mini‐open carpal tunnel release
no estimate extracted4 studies · 274 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency
Major complications (events)
Endoscopic vs open or mini‐open carpal tunnel release
RR 1 [0.38, 2.64]15 studies · 1508 participantsLow
Downgraded: risk of bias
Minor complications events with minor complications
Endoscopic vs open or mini‐open carpal tunnel release
RR 0.55 [0.38, 0.81]18 studies · 1786 participantsLow
Downgraded: risk of bias