Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

929 questions · 946 findings · 295 reviews · Headline outcomes only

No studies found 150 · 15.9%GRADE not reported 47 · 5%Very low 312 · 33%Low 262 · 27.7%Moderate 138 · 14.6%High 37 · 3.9%

Intervention not reported

Number of subjects who had one or more exacerbations over the study period in children and adolescents ( · Adults and children with asthma

The intervention showed no clear difference in number of subjects who had one or more exacerbations over the study… (moderate certainty).

1 finding from 1 review

Intervention not reported

Contrast threshold loss ‐0.15 log units or more at 1 year · patients with choroidal neovascularisation secondary to age‐related macular degeneration

The intervention showed no clear difference in contrast threshold loss ‐0.15 log units or more at 1 year (moderate certainty).

1 finding from 1 review

Intervention not reported

Reading speed 40 word/minute or more after 1 year · patients with choroidal neovascularisation secondary to age‐related macular degeneration

The intervention showed no clear difference in reading speed 40 word/minute or more after 1 year (high certainty).

1 finding from 1 review

Photodynamic therapy with verteporfin vs photodynamic therapy with 5% dextrose

BCVA: loss of 15 or more ETDRS letters · people with neovascular age‐related macular degeneration

Photodynamic therapy with verteporfin leads to lower loss of 3 or more lines (15 or more letters) visual acuity ETDRS chart compared with photodynamic therapy with 5% dextrose (high certainty).

1 finding from 1 review

Photodynamic therapy with verteporfin vs photodynamic therapy with 5% dextrose

Six or more lines visual acuity lost · people with neovascular age‐related macular degeneration

Photodynamic therapy with verteporfin leads to lower loss of 6 or more lines (30 or more letters) visual acuity ETDRS chart compared with photodynamic therapy with 5% dextrose (high certainty).

1 finding from 1 review

Photodynamic therapy with verteporfin vs photodynamic therapy with 5% dextrose

Gain of 3 or more lines of visual acuity · people with neovascular age‐related macular degeneration

Photodynamic therapy with verteporfin leads to higher gain of 3 or more lines (15 or more letters) compared with photodynamic therapy with 5% dextrose (high certainty).

1 finding from 1 review

Anticipated low‐responders: higher vs lower dose of FSH

300/450 IU vs 150 IU · women undergoing IVF/ICSI who are anticipated to have a low‐response to stimulation based on one or more ORT measure

Anticipated low responders: higher showed no clear difference in 300/450 IU vs 150 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated low‐responders: higher vs lower dose of FSH

400/450 IU vs 300 IU · women undergoing IVF/ICSI who are anticipated to have a low‐response to stimulation based on one or more ORT measure

Anticipated low responders: higher showed no clear difference in 400/450 IU vs 300 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Anticipated low‐responders: higher vs lower dose of FSH

IU vs 450 IU · women undergoing IVF/ICSI who are anticipated to have a low‐response to stimulation based on one or more ORT measure

Anticipated low responders: higher showed no clear difference in IU vs 450 IU compared with lower dose of FSH (low certainty).

1 finding from 1 review

Attention deficit hyperactivity disorder (ADHD)‐related drugs vs placebo

Aggression · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

The review found no eligible studies for this question.

1 finding from 1 review

Attention deficit hyperactivity disorder (ADHD)‐related drugs vs placebo

Adverse effects · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

It is very uncertain whether attention deficit hyperactivity disorder (ADHD)‐related drugs changes adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Atypical antipsychotics vs placebo

Adverse effects (AEs) · participants (any age) with a clinical diagnosis of ASD who have displayed one or more unwanted or challenging behaviours at baseline…

Atypical antipsychotics may leads to higher adverse effects (AEs) compared with placebo (low certainty).

1 finding from 1 review