Cochrane · systematic review · CD006931
Submacular surgery for choroidal neovascularisation secondary to age‐related macular degeneration
Giansanti, F, Eandi, CM, Virgili, G · Cochrane Database of Systematic Reviews · 2009 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 1 · 14.3%High 4 · 57.1%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Comparison
Population: patients with choroidal neovascularisation secondary to age‐related macular degeneration
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Visual loss of 2+ lines at 1 year | RR 0.96 [0.84, 1.09] | 2 studies · 715 participants | High |
Visual gain of 2+ lines at 1 year | RR 1.06 [0.75, 1.5] | 2 studies · 715 participants | Low |
Contrast threshold loss ‐0.15 log units or more at 1 year | RR 0.8 [0.63, 1.02] | 2 studies · 689 participants | Moderate |
Reading speed 40 word/minute or more after 1 year | RR 0.88 [0.64, 1.2] | 2 studies · 692 participants | High |
Loss of 6+ points of overall NEI‐VFQ score at 1 year | RR 1.35 [1.09, 1.68] | 2 studies · 689 participants | Low Downgraded: risk of bias |
Adverse events: cataract surgery at 1 year | RR 8.69 [4.06, 18.61] | 2 studies · 632 participants | High |
Adverse events: retinal detachment during | RR 6.13 [2.81, 13.38] | 2 studies · 790 participants | High |