Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

929 questions · 946 findings · 295 reviews · Headline outcomes only

No studies found 150 · 15.9%GRADE not reported 47 · 5%Very low 312 · 33%Low 262 · 27.7%Moderate 138 · 14.6%High 37 · 3.9%

Asthma Clinics (Intervention) vs controls

Number of participants experiencing one or more episodes requiring ED visit · people with asthma

It is very uncertain whether asthma Clinics (Intervention) changes A&E visits Number of people experiencing one or more A&E visit compared with controls (very low certainty).

1 finding from 1 review

Asthma Clinics (Intervention) vs controls

Hospital admissions · people with asthma

Asthma Clinics (Intervention) showed no clear difference in hospital admissions Number of people experiencing one or more… compared with controls (low certainty).

1 finding from 1 review

Intervention not reported

Readmission to hospital, inpatient. Number of people experiencing one or more readmissions ( · exacerbations of COPD

The intervention probably leads to lower readmission to hospital, inpatient. Number of people experiencing… (moderate certainty).

1 finding from 1 review

Intervention not reported

More than 50% improvement in pure‐tone average threshold Risk ratio · patients with idiopathic sudden sensorineural hearing loss or tinnitus

The intervention showed no clear difference in more than 50% improvement in pure‐tone average threshold Risk ratio (moderate certainty).

1 finding from 1 review

Intervention not reported

More than 25% improvement in pure‐tone average threshold Risk ratio · patients with idiopathic sudden sensorineural hearing loss or tinnitus

The intervention probably leads to higher more than 25% improvement in pure‐tone average threshold Risk ratio (moderate certainty).

1 finding from 1 review

Curcumin vs placebo

Relapse at 6 months Clinical Disease Activty Index more than 42 · Maintenance of remission in ulcerative colitis

Curcumin showed no clear difference in relapse at 6 months Clinical Disease Activty Index more than 42 compared with placebo (low certainty).

1 finding from 1 review

Curcumin vs placebo

Relapse at 12 months Clinical Disease Activty Index more than 42 · Maintenance of remission in ulcerative colitis

Curcumin showed no clear difference in relapse at 12 months Clinical Disease Activty Index more than 42 compared with placebo (low certainty).

1 finding from 1 review

Tiotropium vs long‐acting beta‐agonists

Hospitalisations, number of participants with 1 or more exacerbations · patients with stable chronic obstructive pulmonary disease and > 10 pack years smoking history

Tiotropium probably leads to lower patients with 1 or more exacerbations compared with long‐acting beta‐agonists (moderate certainty).

1 finding from 1 review

Intervention not reported

A significant 14% reduction in mean speeds compared to control sites. The proportion of vehicles exceeding the speed limit by more than 10mph decreased by 82%.
1 finding from 1 review

Intervention not reported

Speed outcomes measured: Mean speed, 85th percentile speed, percentage of vehicles over the speed limit and percentage exceeding the speed limit by more than 15mph. Speed results across all new camera sites included a 2.3mph reduction (6% reductio...
1 finding from 1 review

Intervention not reported

A 30% reduction in vehicles exceeding the speed limit, and a 43% reduction in vehicles exceeding the speed limit by more than 15 mph. Time over distance cameras were shown to be particularly effective (around 100% reduction) at reducing speeds exc...

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Weight: Gain‐more than or equal to 7% from baseline · patients with people with schizophrenia who have neuroleptic‐induced weight or metabolic problems

The intervention showed no clear difference in weight: Gain‐more than or equal to 7% from baseline (moderate certainty).

1 finding from 1 review

CHLORPROMAZINE vs haloperidol

Global outcome: Number of additional injections ‐ 5 or more · patients with psychosis‐induced aggression or agitation

It is very uncertain whether CHLORPROMAZINE changes global outcome: Number of additional injections ‐ 5 or more compared with HALOPERIDOL (very low certainty).

1 finding from 1 review

Intervention not reported

Number of subjects who had one or more exacerbations over the study period in adults ( · Adults and children with asthma

The intervention showed no clear difference in number of subjects who had one or more exacerbations over the study… (moderate certainty).

1 finding from 1 review