Intervention not reported
Mortality Beyond the early postoperative period (> 30 days) · participants with hydrocephalus
1 finding from 1 review
- no estimate extracted1 study · 90 participantsVery low
Findings
What do systematic reviews say?
2,087 questions · 2,360 findings · 390 reviews
No studies found 224 · 9.5%GRADE not reported 603 · 25.6%Very low 555 · 23.5%Low 548 · 23.2%Moderate 312 · 13.2%High 118 · 5%
Transverse groin incision vs vertical groin incision
Graft infection · patients undergoing surgery with femoral artery approach
The review found no eligible studies for this question.
1 finding from 1 review
- Transverse versus vertical groin incision for femoral artery approach 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Strategies to increase use of antenatal corticosteroids vs usual care
Offspring mortality, early neurodevelopmental morbidity or late neurodevelopmental morbidity · women at risk of preterm birth
The review found no eligible studies for this question.
1 finding from 1 review
- Strategies for optimising antenatal corticosteroid administration for women with anticipated preterm birth 2020 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Combined index test: visual examination + radiograph + DIAGNOdent (Alomari 2015) vs Reference standard: histology
Specificity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
- Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies)Specificity 0.65 [0.38, 0.86]1 studyGRADE not reported
Blue fluorescence devices (VistaProof, SoproLife, Spectra; wavelength 400-450 nm) vs Reference standard (histology, excavation, or enhanced visual examination)
Diagnostic odds ratio (DOR) for detection of early enamel caries (D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
- Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies)DOR 18.47 [10.59, 32.20]20 studiesGRADE not reported
All fluorescence-based devices (red, blue, and green fluorescence combined) vs Reference standard (histology, excavation, or enhanced visual examination)
Diagnostic odds ratio (DOR) by subgroup: High dentine-caries prevalence (>=35%) (detection of early enamel caries, D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
- Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · High dentine-caries prevalence (>=35%)DOR 14.59 [9.18, 23.22]Studies not reportedGRADE not reported
All fluorescence-based devices (red, blue, and green fluorescence combined) vs Reference standard (histology, excavation, or enhanced visual examination)
Diagnostic odds ratio (DOR) by subgroup: Primary dentition (detection of early enamel caries, D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
- Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Primary dentitionDOR 12.34 [8.44, 18.04]Studies not reportedGRADE not reported
MidWest (DENTSPLY; red fluorescence, red/green light and sound signal) vs Reference standard (histology, excavation, or enhanced visual examination)
Diagnostic accuracy (sensitivity and specificity) for detection of early enamel caries (D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
- Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies)Analysed as a separate index test (coupled forest plot and SROC plot, Figure 22 / Figure 23; Appendix 5); no summary DOR or sensitivity/specificity point reported numerically in the text. 4 datasets, 356 tooth sites.4 studiesGRADE not reported
All fluorescence-based devices (red, blue, and green fluorescence combined) vs Reference standard (histology, excavation, or enhanced visual examination)
Diagnostic odds ratio (DOR) by subgroup: Multiple sites per tooth (detection of early enamel caries, D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
- Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Multiple sites per toothDOR 9.46 [5.91, 15.14]18 studiesGRADE not reported
All fluorescence-based devices (red, blue, and green fluorescence combined) vs Reference standard (histology, excavation, or enhanced visual examination)
Diagnostic odds ratio (DOR) by subgroup: Smooth or secondary-caries surfaces (detection of early enamel caries, D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
- Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Smooth or secondary-caries surfacesDOR 13.41 [5.58, 32.25]Studies not reportedGRADE not reported
All fluorescence-based devices (red, blue, and green fluorescence combined) vs Reference standard (histology, excavation, or enhanced visual examination)
Diagnostic odds ratio (DOR) by subgroup: Proximal surfaces (detection of early enamel caries, D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
- Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Proximal surfacesDOR 13.06 [7.52, 22.67]Studies not reportedGRADE not reported
All fluorescence-based devices (red, blue, and green fluorescence combined) vs Reference standard (histology, excavation, or enhanced visual examination)
Diagnostic odds ratio (DOR) by subgroup: Occlusal surfaces (detection of early enamel caries, D1 threshold) · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…
1 finding from 1 review
- Fluorescence devices for the detection of dental caries 2020 · Cochrane All outcomesUp to 3 months between index test and reference standard (in vivo studies) · Occlusal surfacesDOR 14.29 [10.92, 18.72]Studies not reportedGRADE not reported
Inositol supplementation to preterm infants (repeat doses in any amount and any duration of treatment) vs control
Sepsis · preterm infants with or at risk of respiratory distress syndrome
Inositol supplementation to preterm infants (repeat doses in any… showed no clear difference in sepsis (early or late onset) compared with control (moderate certainty).
1 finding from 1 review
- Inositol in preterm infants at risk for or having respiratory distress syndrome 2019 · Cochrane Headline outcomes onlyRR 1.21 [0.95, 1.54]4 studies · 1067 participantsModerate
Antidepressants plus benzodiazepines vs antidepressants alone
Depression severity ‐ mean EPDS score (early phase, < 5 weeks) · patients with major depression
1 finding from 1 review
- Antidepressants plus benzodiazepines for adults with major depression 2019 · Cochrane Headline outcomes onlyno estimate extracted10 studies · 598 participantsModerate
Antidepressants plus benzodiazepines vs antidepressants alone
Anxiety · patients with major depression
1 finding from 1 review
- Antidepressants plus benzodiazepines for adults with major depression 2019 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 129 participantsVery low
INTEGRATED MODELS OF CARE vs usual care
Lost to treatment · people with both severe mental illness and substance misuse
Integrated models of care showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).
1 finding from 1 review
- Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes onlyRR 1.09 [0.82, 1.45]3 studies · 603 participantsLow
CBT vs usual care
Lost to treatment · people with both severe mental illness and substance misuse
Cognitive behavioural therapy showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).
1 finding from 1 review
- Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes onlyRR 1.12 [0.44, 2.86]2 studies · 152 participantsLow
CONTINGENCY MANAGEMENT vs usual care
Lost to treatment · people with both severe mental illness and substance misuse
Contingency management probably leads to higher leaving the study early: Lost to treatment compared with standard care (moderate certainty).
1 finding from 1 review
- Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes onlyRR 1.55 [1.13, 2.11]2 studies · 255 participantsModerate
SKILLS TRAINING vs usual care
Lost to treatment · people with both severe mental illness and substance misuse
It is very uncertain whether skills training changes leaving the study early: Lost to treatment compared with standard care (very low certainty).
1 finding from 1 review
- Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes onlyRR 1.42 [0.2, 10.1]3 studies · 122 participantsVery low
COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care
Lost to treatment · people with both severe mental illness and substance misuse
Cognitive behavioural therapy + motivational interviewing showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).
1 finding from 1 review
- Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes onlyRR 0.99 [0.62, 1.59]1 study · 327 participantsLow