Cochrane · systematic review · CD012726

Ventriculo‐peritoneal shunting devices for hydrocephalus

Garegnani, L, Franco, JVA, Ciapponi, A, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
20
current version
GRADE rated
13
No studies
6
Included studies
NR
No studies 6 · 30%Ungraded 1 · 5%Very low 4 · 20%Low 9 · 45%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Standard valve compared to anti‐syphon valve for hydrocephalus

Population: participants with hydrocephalus
5 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment failure: morbidity associated with shunt placement that led to shunt revision
Standard valve vs anti‐syphon valve
no estimate extracted3 studies · 296 participantsVery low
Downgraded: risk of bias
Adverse events: morbidity related to the shunt placement that has not led to shunt revision
Standard valve vs anti‐syphon valve
no estimate extracted1 study · 229 participantsLow
Downgraded: risk of bias
Mortality In the early postoperative period (≤ 30 days)
Standard valve vs anti‐syphon valve
no estimate extracted1 study · 229 participantsLow
Downgraded: risk of bias
Mortality Beyond the early postoperative period (> 30 days)
Standard valve vs anti‐syphon valve
no estimate extracted1 study · 229 participantsLow
Downgraded: risk of bias
Quality of life
Standard valve vs anti‐syphon valve
no estimate extractedNRNo studies

Comparison between different types of standard valves

Population: participants with hydrocephalus
5 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment failure: morbidity associated with shunt placement that led to shunt revision
no estimate extracted2 studies · 174 participantsVery low
Downgraded: risk of bias
Adverse events: morbidity related to the shunt placement that has not led to shunt revision
no estimate extracted0 studies · 0 participantsUngraded
Mortality In the early postoperative period (≤ 30 days)
no estimate extracted2 studies · 174 participantsVery low
Downgraded: risk of bias
Mortality Beyond the early postoperative period (> 30 days)
no estimate extracted1 study · 90 participantsVery low
Downgraded: risk of bias
Quality of life
no estimate extractedNRNo studies

Standard valve compared to self‐adjusting CSF flow‐regulating valve for hydrocephalus

Population: participants with hydrocephalus
5 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment failure: morbidity associated with shunt placement that led to shunt revision
Standard valve vs self‐adjusting CSF flow‐regulating valve
no estimate extracted1 study · 229 participantsLow
Downgraded: risk of bias
Adverse events: morbidity related to the shunt placement that has not led to shunt revision
Standard valve vs self‐adjusting CSF flow‐regulating valve
no estimate extracted1 study · 229 participantsLow
Downgraded: risk of bias
Mortality In the early postoperative period (≤ 30 days)
Standard valve vs self‐adjusting CSF flow‐regulating valve
no estimate extracted1 study · 229 participantsLow
Downgraded: risk of bias
Mortality Beyond the early postoperative period (> 30 days)
Standard valve vs self‐adjusting CSF flow‐regulating valve
no estimate extracted1 study · 229 participantsLow
Downgraded: risk of bias
Quality of life
Standard valve vs self‐adjusting CSF flow‐regulating valve
no estimate extractedNRNo studies

External differential programmable pressure valve compared to non‐programmable valves

Population: participants with hydrocephalus
5 questions
OutcomeEffectEvidenceStatus / GRADE
Treatment failure: morbidity associated with shunt placement that led to shunt revision
External differential programmable pressure valve vs non‐programmable valves
no estimate extracted1 study · 377 participantsLow
Downgraded: risk of bias
Adverse events: morbidity related to the shunt placement that has not led to shunt revision
External differential programmable pressure valve vs non‐programmable valves
no estimate extracted1 study · 377 participantsLow
Downgraded: risk of bias
Mortality In the early postoperative period (≤30 days)
External differential programmable pressure valve vs non‐programmable valves
no estimate extractedNRNo studies
Mortality Beyond the early postoperative period (>30 days)
External differential programmable pressure valve vs non‐programmable valves
no estimate extractedNRNo studies
Quality of life
External differential programmable pressure valve vs non‐programmable valves
no estimate extractedNRNo studies