Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,679 questions · 1,720 findings · 335 reviews · Headline outcomes only

No studies found 192 · 11.2%GRADE not reported 75 · 4.4%Very low 526 · 30.6%Low 504 · 29.3%Moderate 305 · 17.7%High 118 · 6.9%

Corticosteroids vs control

Early clinical failure ‐ children · people with community‐acquired pneumonia

Corticosteroids leads to lower early clinical failure ‐ children compared with control (high certainty).

1 finding from 1 review

CHLORPROMAZINE LOW DOSE (≤ 400 mg/day) vs HIGH DOSE (> 800 mg/day ‐ all medium term)

Behaviour: deterioration of behaviour (categorised as reason to leave early) · schizophrenia

CHLORPROMAZINE LOW DOSE (≤ 400 mg/day) may leads to higher behaviour: deterioration of behaviour (categorised as reason to… compared with HIGH DOSE (> 800 mg/day ‐ all medium term) (low certainty).

1 finding from 1 review

One‐incision vs two‐incision techniques

IKDC knee examination grade normal (grade A) or nearly normal (grade B) ‐ Intermediate/long‐term · adults undergoing arthroscopically assisted ACL reconstruction1

It is very uncertain whether one‐incision changes objective functional knee assessments using IKDC10 (intermediate… compared with two‐incision techniques (very low certainty).

1 finding from 1 review