Cochrane · systematic review · CD007720

Corticosteroids for pneumonia

Stern, A, Skalsky, K, Avni, T, et al. · Cochrane Database of Systematic Reviews · 2017 · Cochrane Library

Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 4 · 57.1%High 3 · 42.9%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Corticosteroids compared to control for pneumonia

Population: people with community‐acquired pneumonia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Mortality ‐ adults
Corticosteroids vs control
RR 0.66 [0.47, 0.92]11 studies · 1863 participantsModerate
Downgraded: risk of bias
Mortality ‐ adults ‐ severe CAP
Corticosteroids vs control
RR 0.58 [0.4, 0.84]9 studies · 995 participantsModerate
Downgraded: risk of bias
Mortality ‐ adults ‐ non‐severe CAP
Corticosteroids vs control
RR 0.95 [0.45, 2]4 studies · 868 participantsModerate
Downgraded: imprecision
Early clinical failure ‐ adults
Corticosteroids vs control
RR 0.4 [0.23, 0.7]6 studies · 1324 participantsModerate
Downgraded: risk of bias, inconsistency
Early clinical failure ‐ adults ‐ severe CAP
Corticosteroids vs control
RR 0.32 [0.15, 0.7]5 studies · 419 participantsHigh
Early clinical failure ‐ adults ‐ non‐severe CAP
Corticosteroids vs control
RR 0.68 [0.56, 0.83]2 studies · 905 participantsHigh
Early clinical failure ‐ children
Corticosteroids vs control
RR 0.41 [0.24, 0.7]2 studies · 88 participantsHigh