What do systematic reviews say?

Omega‐3 vs placebo

Omega 3 fatty acids probably leads to higher loss of 3 or more lines of VA at 24 months compared with placebo (moderate certainty).

• Omega 3 fatty acids for preventing or slowing the progression of age‐related macular degeneration 2015 · Cochrane Headline outcomes only
  RR 1.14
  1 study · 236 participants
  Moderate
• Omega 3 fatty acids for preventing or slowing the progression of age‐related macular degeneration 2015 · Cochrane Headline outcomes only
  RR 1.25
  1 study · 230 participants
  Moderate

Indacaterol vs placebo

Indacaterol leads to lower number of participants experiencing 1 or more exacerbations compared with placebo (high certainty).

• Indacaterol, a once‐daily beta₂‐agonist, versus twice‐daily beta₂‐agonists or placebo for chronic obstructive… 2015 · Cochrane Headline outcomes only
  OR 0.81 [0.7, 0.94]
  7 studies · 4807 participants
  High

Ruxolitinib vs placebo

Ruxolitinib may leads to higher health‐related quality of life Patients that achieved a reduction of… compared with placebo (low certainty).

• Janus kinase‐1 and Janus kinase‐2 inhibitors for treating myelofibrosis 2015 · Cochrane Headline outcomes only
  RR 8.82 [4.4, 17.69]
  1 study · 309 participants
  Low

FAE vs placebo

• Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 418 participants
  Low

FAE vs MTX

• Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 51 participants
  Very low

Intervention not reported

• Telerehabilitation for persons with multiple sclerosis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 82 participants
  Low

Intervention not reported

• Telerehabilitation for persons with multiple sclerosis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 299 participants
  Low

PFMT added to bladder training vs bladder training alone

The review found no eligible studies for this question.

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

PFMT added to vaginal cones vs vaginal cones alone

The review found no eligible studies for this question.

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

PFMT added to electrical stimulation vs electrical stimulation alone (excluding implanted electrodes)

The review found no eligible studies for this question.

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

PFMT added to magnetic stimulation vs magnetic stimulation alone

The review found no eligible studies for this question.

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

PFMT added to continence pessary vs continence pessary alone

The review found no eligible studies for this question.

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

PFMT added to drug therapy vs drug therapy alone

The review found no eligible studies for this question.

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

PFMT prior to surgical intervention vs surgical intervention alone

The review found no eligible studies for this question.

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

PFMT added to HSGS vs HSGS alone

The review found no eligible studies for this question.

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

PFMT added to lifestyle intervention vs lifestyle intervention alone

The review found no eligible studies for this question.

• Pelvic floor muscle training added to another active treatment versus the same active treatment alone for urinary… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

It is very uncertain whether the intervention changes progression (increase in maximal keratometry of 1.5 dioptres or more) (very low certainty).

• Corneal collagen cross‐linking for treating keratoconus 2015 · Cochrane Headline outcomes only
  RR 0.12 [0.01, 2]
  1 study · 19 participants
  Very low

Rapid COJEC vs standard induction therapies

• Rapid COJEC versus standard induction therapies for high‐risk neuroblastoma 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 248 participants
  Low

One intervention vs no intervention

One intervention leads to higher ANC coverage: four or more visits compared with no intervention (high certainty).

• Health system and community level interventions for improving antenatal care coverage and health outcomes 2015 · Cochrane Headline outcomes only
  OR 1.11 [1.01, 1.22]
  10 studies · 45022 participants
  High

Combination of interventions vs no intervention

Combination of interventions probably leads to higher ANC coverage: one or more visits compared with no intervention (moderate certainty).

• Health system and community level interventions for improving antenatal care coverage and health outcomes 2015 · Cochrane Headline outcomes only
  OR 1.79 [1.47, 2.17]
  5 studies · 12426 participants
  Moderate