Findings

What do systematic reviews say?

1,247 questions · 1,321 findings · 334 reviews

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No studies found 73 · 5.5%GRADE not reported 31 · 2.3%Very low 500 · 37.9%Low 406 · 30.7%Moderate 247 · 18.7%High 64 · 4.8%

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs placebo

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs lidocaine intraperitoneal instillation alone

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Combination of lidocaine intraperitoneal instillation plus intramuscular morphine vs IM morphine

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Lidocaine instillation vs placebo

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Intramuscular morphine vs placebo

Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Robotic‐assisted laparoscopic vs open radical cystectomy

Quality of life (higher scores indicate better quality of life) · bladder cancer in adults

1 finding from 1 review

Robotic versus open radical cystectomy for bladder cancer in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 270 participants
Low

Aerobic exercise and strength training vs usual care

Change from baseline in 6MWT (metres) · children and adults with SMA type 3

1 finding from 1 review

Physical exercise training for type 3 spinal muscular atrophy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 12 participants
Very low

Omega‐3 vs placebo

Mental state: psychotic symptoms Average total score (PANSS, higher score = worse, scale from 30‐210) Long‐term (up to 7 years) · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 81 participants
Low

Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment

Global effect: 1a. Medium‐term ‐ Average end point score on various outcomes ‐ CGI‐severity (low = favourable) ( · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment

Mental state: psychosis risk symptoms SOPS total (higher score = worse, scale from: 0‐114) · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment

Weight gain · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

Group A: amino acids vs placebo

Mental state: psychosis risk symptoms SOPS total (higher score = worse, scale from: 0‐114) · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 8 participants
Very low

Group B cognitive behavioural therapy: cognitive behavioural therapy + supportive therapy vs supportive therapy

Mental state · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 68 participants
Very low

Group B cognitive behavioural therapy: cognitive behavioural therapy + supportive therapy vs supportive therapy

Quality of Life Manchester Short Assessment (MANSA) · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 140 participants
Very low

Group B cognitive behavioural therapy: cognitive behavioural therapy + risperidone vs placebo and cognitive and behavioural therapies

Global state: Response ‐ proxy outcome ‐ mental state: 1. General ‐ average score (Brief Psychiatric Rating Scale by over 24 weeks · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 51 participants
Very low

Group B cognitive behavioural therapy: cognitive behavioural therapy + risperidone vs placebo and cognitive and behavioural therapies

QoL · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 51 participants
Very low

Group B cognitive behavioural therapy: cognitive behavioural therapy (specific preventive intervention) + needs‐based intervention + risperidone vs needs‐based intervention

Mental state: psychopathology Total endpoint data, BPRS (higher score = worse, scale from: 0‐126) · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Group B cognitive behavioural therapy: cognitive behavioural therapy (specific preventive intervention) + needs‐based intervention + risperidone vs needs‐based intervention

QoL · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Group C cognitive behavioural therapy: cognitive behavioural therapy + placebo vs placebo or supportive treatment

Global state: Response ‐ proxy outcome ‐ mental state: 1. General ‐ average score (Brief Psychiatric Rating Scale by over 24 weeks · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 45 participants
Very low

Group C cognitive behavioural therapy: cognitive behavioural therapy + placebo vs placebo or supportive treatment

Quality of life QLS · people in the prodromal stage of psychosis

1 finding from 1 review

Interventions for prodromal stage of psychosis 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 44 participants
Very low