Findings

What do systematic reviews say?

1,230 questions · 1,303 findings · 326 reviews · Headline outcomes only

Sort:Best matchNewest Highest certainty Download CSV

No studies found 73 · 5.6%GRADE not reported 21 · 1.6%Very low 497 · 38.1%Low 403 · 30.9%Moderate 245 · 18.8%High 64 · 4.9%

Oral long‐chain omega‐3 PUFAs vs oral omega‐6 PUFAs

Aqueous tear production · people with dry eyea

Oral long‐chain omega‐3 PUFAs showed no clear difference in change in Schirmer test (aqueous tear production, measured in mm/5… compared with oral omega‐6 PUFAs (low certainty).

1 finding from 1 review

Omega‐3 and omega‐6 polyunsaturated fatty acids for dry eye disease 2019 · Cochrane Headline outcomes only
MD 2.6
5 studies · 1205 participants
Low

Oral long‐chain omega‐3 PUFAs vs oral omega‐6 PUFAs

Tear film stability · people with dry eyea

1 finding from 1 review

Omega‐3 and omega‐6 polyunsaturated fatty acids for dry eye disease 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1205 participants
Low

Oral long‐chain omega‐3 PUFAs vs placebo or no treatment

Aqueous tear production · people with dry eyea

Oral long‐chain omega‐3 PUFAs (ie, EPA and DHA) showed no clear difference in change in Schirmer test (aqueous tear production, measured in mm/5… compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Omega‐3 and omega‐6 polyunsaturated fatty acids for dry eye disease 2019 · Cochrane Headline outcomes only
MD 0.68
7 studies · 1730 participants
Moderate

Oral long‐chain omega‐3 PUFAs vs placebo or no treatment

Tear film stability · people with dry eyea

1 finding from 1 review

Omega‐3 and omega‐6 polyunsaturated fatty acids for dry eye disease 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1640 participants
Low

Combined oral omega‐3 and omega‐6 PUFAs vs placebo

Aqueous tear production · people with dry eyea

Combined oral omega‐3 and omega‐6 PUFAs showed no clear difference in schirmer test (aqueous tear production, measured in mm/5 min, with… compared with placebo (moderate certainty).

1 finding from 1 review

Omega‐3 and omega‐6 polyunsaturated fatty acids for dry eye disease 2019 · Cochrane Headline outcomes only
MD 0.66
4 studies · 455 participants
Moderate

Intervention not reported

Achievement of at least 50% reduction in headache severity Post‐treatment Higher scores indicate more children with reduced headache · children or adolescents with headaches

It is very uncertain whether the intervention changes achievement of at least 50% reduction in headache severity… (very low certainty).

1 finding from 1 review

Psychological therapies (remotely delivered) for the management of chronic and recurrent pain in children and… 2019 · Cochrane Headline outcomes only
RR 2.02 [1.35, 3.01]
7 studies · 379 participants
Very low

Health‐promotion interventions within community pharmacy vs usual treatment alone

Pharmacy user health‐related behaviour3 (Higher scores indicate a better outcome) · community pharmacy workers (examples pharmacists, counter assistants etc), community pharmacy users

1 finding from 1 review

Community pharmacy interventions for health promotion: effects on professional practice and health outcomes 2019 · Cochrane Headline outcomes only
no estimate extracted
2138 participants
Moderate

Health‐promotion interventions within community pharmacy vs usual treatment alone

Pharmacy user quality of life6 (Higher scores indicate better quality of life) · community pharmacy workers (examples pharmacists, counter assistants etc), community pharmacy users

1 finding from 1 review

Community pharmacy interventions for health promotion: effects on professional practice and health outcomes 2019 · Cochrane Headline outcomes only
no estimate extracted
2687 participants
Moderate

Acetyl‐L‐carnitine vs placebo

Pain at 6 months or more; all doses Assessed by change from baseline, using a 0‐ to 100‐mm VAS, where higher scores indicate more pain) · people with diabetic peripheral neuropathy

1 finding from 1 review

Acetyl‐L‐carnitine for the treatment of diabetic peripheral neuropathy 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 540 participants
Very low

Acetyl‐L‐carnitine vs methylcobalamin

Symptom quality and severity Assessed by NSS score (range of possible scores 0 to 9; higher scores indicate more symptoms) · the treatment of diabetic peripheral neuropathy

1 finding from 1 review

Acetyl‐L‐carnitine for the treatment of diabetic peripheral neuropathy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 232 participants
Low

Intervention not reported

Disability (measured by the Glasgow Outcome Scale; higher score is better) · adults presenting with elevated intracranial pressure secondary to a traumatic brain injury

1 finding from 1 review

Indomethacin for intracranial hypertension secondary to severe traumatic brain injury in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

EMLA vs placebo

Pain during abdominal entry (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia

1 finding from 1 review

Interventions for intra‐operative pain relief during postpartum mini‐laparotomy tubal ligation 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low