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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,645 questions in 107 reviews · Wounds
current versionsNo studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Hydrogel dressings vs hydrogel dressings Adverse events (wound‐related pain) · people with pressure ulcers Hydrogel dressings for treating pressure ulcers (2015) · Cochrane | RR 1.92 [0.01, 2.44] | 1 study · 47 participants | Low |
Hydrogel dressings vs hydrogel dressings Adverse events (pain on dressing removal) · people with pressure ulcers Hydrogel dressings for treating pressure ulcers (2015) · Cochrane | RR 1.19 [0.8, 1.76] | 1 study · 42 participants | Low |
Hydrogel dressings vs foam dressing Proportion of ulcers completely healed · people with pressure ulcers Hydrogel dressings for treating pressure ulcers (2015) · Cochrane | no estimate extracted | 1 study · 34 participants | Ungraded |
Alginate dressing followed by hydrocolloid dressing vs hydrocolloid dressing alone Change in wound size · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | no estimate extracted | 1 study · 110 participants | Very low |
Alginate vs radiant heat system Change in wound size · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | no estimate extracted | 1 study · 1105 participants | Very low |
Alginate vs radiant heat system Adverse event (pain) · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | no estimate extracted | 1 study · 50 participants | Very low |
Alginate dressing followed by hydrocolloid dressing vs hydrocolloid dressing alone Wound infection · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | RR 2.79 [0.12, 67.1] | 1 study · 110 participants | Very low |
Alginate dressing followed by hydrocolloid dressing vs hydrocolloid dressing alone Adverse events · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | RR 1.12 [0.36, 3.44] | 1 study · 110 participants | Low |
Intervention NR Complete wound healing · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | RR 1.5 [0.17, 12.94] | 1 study · 36 participants | Very low |
Intervention NR Adverse events · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | RR 0.5 [0.12, 2.12] | 1 study · 36 participants | Very low |
Alginate vs dextranomer paste Wound infection · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | RR 0.96 [0.14, 6.51] | 1 study · 92 participants | Very low |
Alginate vs dextranomer paste Adverse events · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | RR 0.38 [0.13, 1.13] | 1 study · 92 participants | Very low |
Silver‐alginate vs plain alginate Change in wound size · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | no estimate extracted | 1 study · 110 participants | Very low |
Silver‐alginate vs plain alginate Wound infection · patients with pressure ulcers Alginate dressings for treating pressure ulcers (2015) · Cochrane | no estimate extracted | 1 study · 28 participants | Very low |
Negative pressure wound therapy vs standard care Time to healing · people with leg ulcers undergoing a punch skin‐graft Negative pressure wound therapy for treating leg ulcers (2015) · Cochrane | HR 3.2 [1.7, 6.2] | 1 study · 60 participants | Low |
Negative pressure wound therapy vs standard care Proportion of wounds healed · people with leg ulcers undergoing a punch skin‐graft Negative pressure wound therapy for treating leg ulcers (2015) · Cochrane | RR 1 [0.91, 1.1] | 1 study · 60 participants | Low |
Negative pressure wound therapy vs standard care Adverse events · people with leg ulcers undergoing a punch skin‐graft Negative pressure wound therapy for treating leg ulcers (2015) · Cochrane | no estimate extracted | 0 studies · 1 participants | Ungraded |
Tissue adhesive vs sutures Wound dehiscence · People with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 3.35 [1.53, 7.32] | 10 studies · 736 participants | Low |
High viscosity tissue adhesive vs low viscosity tissue adhesive Wound infection · people with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 0.82 [0.16, 4.31] | 1 study · 148 participants | Very low |
Octylcyanoacrylate vs butylcyanoacrylate Wound dehiscence · people with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 1.46 [0.19, 11] | 2 studies · 80 participants | Low |
Octylcyanoacrylate vs butylcyanoacrylate Wound infection · people with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 0.63 [0.21, 1.88] | 1 study · 37 participants | Low |
Tissue adhesive vs sutures Wound infection · People with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 1.72 [0.92, 3.16] | 10 studies · 744 participants | Very low |
Tissue adhesive vs adhesive tape Wound dehiscence · people with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 0.96 [0.06, 14.55] | 1 study · 50 participants | Low |
Tissue adhesive vs adhesive tape Wound infection · people with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 1.37 [0.39, 4.81] | 3 studies · 190 participants | Low |
Tissue adhesive vs staples Wound dehiscence · people with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 0.53 [0.05, 5.33] | 1 study · 37 participants | Low |
Tissue adhesive vs staples Wound infection · people with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 1.39 [0.3, 6.54] | 3 studies · 250 participants | Very low |
Tissue adhesive vs other methods Wound dehiscence · people with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 0.55 [0.13, 2.38] | 1 study · 209 participants | Low |
Tissue adhesive vs other methods Wound infection · people with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 0.41 [0.11, 1.6] | 1 study · 209 participants | Low |
High viscosity tissue adhesive vs low viscosity tissue adhesive Wound dehiscence · people with surgical incisions Tissue adhesives for closure of surgical incisions (2014) · Cochrane | RR 3.74 [0.21, 67.93] | 1 study · 148 participants | Very low |
Recombinant human growth hormone vs placebo Healing time of burn wounds in days for adults Recombinant human growth hormone for treating burns and donor sites (2014) · Cochrane | no estimate extracted | 2 studies · 36 participants | Low |
Recombinant human growth hormone vs placebo Donor site healing time in days for adults Recombinant human growth hormone for treating burns and donor sites (2014) · Cochrane | no estimate extracted | 2 studies · 36 participants | Low |
Recombinant human growth hormone vs placebo Donor site healing time in days for children Recombinant human growth hormone for treating burns and donor sites (2014) · Cochrane | no estimate extracted | 2 studies · 73 participants | Low |
Recombinant human growth hormone vs placebo Mortality in adults and children Recombinant human growth hormone for treating burns and donor sites (2014) · Cochrane | RR 0.53 [0.22, 1.29] | 5 studies · 324 participants | Low |
Recombinant human growth hormone vs placebo Septicaemia in adults Recombinant human growth hormone for treating burns and donor sites (2014) · Cochrane | RR 0.61 [0.31, 1.22] | 4 studies · 267 participants | Low |
Recombinant human growth hormone vs placebo Hyperglycaemia in adults and children Recombinant human growth hormone for treating burns and donor sites (2014) · Cochrane | RR 2.65 [1.68, 4.16] | 5 studies · 340 participants | Low |
Recombinant human growth hormone vs placebo Length of hospital stay in days for adults Recombinant human growth hormone for treating burns and donor sites (2014) · Cochrane | no estimate extracted | 4 studies · 99 participants | Low |
Phototherapy vs control Time to complete healing (weeks) (UV vs control) Scale from: 0 to complete healing · patients being treated for pressure ulcers Phototherapy for treating pressure ulcers (2014) · Cochrane | no estimate extracted | 2 studies · 32 participants | Very low |
Phototherapy vs control Time to complete healing (weeks) (laser vs control) weeks. Scale from: 0 to complete healing. · patients being treated for pressure ulcers Phototherapy for treating pressure ulcers (2014) · Cochrane | no estimate extracted | 1 study · 8 participants | Very low |
Intervention NR Oedema ‐ Day 1 Scale 1 to 4 · adults undergoing facial plastic surgery Perioperative corticosteroids for preventing complications following facial plastic surgery (2014) · Cochrane | no estimate extracted | 2 studies · 60 participants | Low |
Intervention NR Ecchymosis ‐ Day 1 Scale 1 to 4 · adults undergoing facial plastic surgery Perioperative corticosteroids for preventing complications following facial plastic surgery (2014) · Cochrane | no estimate extracted | 2 studies · 60 participants | Low |
Continuous skin sutures vs interrupted skin sutures Superficial surgical site infection · participants with non‐obstetric surgery Continuous versus interrupted skin sutures for non‐obstetric surgery (2014) · Cochrane | RR 0.73 [0.4, 1.33] | 4 studies · 602 participants | Very low |
Continuous skin sutures vs interrupted skin sutures Superficial wound dehiscence · participants with non‐obstetric surgery Continuous versus interrupted skin sutures for non‐obstetric surgery (2014) · Cochrane | RR 0.08 [0.02, 0.35] | 4 studies · 625 participants | Low |
Continuous skin sutures vs interrupted skin sutures Hospital stay · participants with non‐obstetric surgery Continuous versus interrupted skin sutures for non‐obstetric surgery (2014) · Cochrane | no estimate extracted | 1 study · 105 participants | Very low |
Subcutaneous closure vs no subcutaneous closure Superficial surgical site infection · participants having non‐caesarean surgery Subcutaneous closure versus no subcutaneous closure after non‐caesarean surgical procedures (2014) · Cochrane | RR 0.84 [0.53, 1.33] | 6 studies · 815 participants | Very low |
Subcutaneous closure vs no subcutaneous closure Superficial wound dehiscence · participants having non‐caesarean surgery Subcutaneous closure versus no subcutaneous closure after non‐caesarean surgical procedures (2014) · Cochrane | RR 0.56 [0.22, 1.41] | 2 studies · 215 participants | Very low |
Subcutaneous closure vs no subcutaneous closure Deep wound dehiscence · participants having non‐caesarean surgery Subcutaneous closure versus no subcutaneous closure after non‐caesarean surgical procedures (2014) · Cochrane | RR 0.25 [0.03, 2.11] | 1 study · 60 participants | Very low |
Subcutaneous closure vs no subcutaneous closure Hospital stay · participants having non‐caesarean surgery Subcutaneous closure versus no subcutaneous closure after non‐caesarean surgical procedures (2014) · Cochrane | no estimate extracted | 3 studies · 434 participants | Very low |
G‐CSF + standard treatment vs usual treatment improvement of infection clinical and microbiological assessment · patients with diabetic foot infection Granulocyte‐colony stimulating factors as adjunctive therapy for diabetic foot infections (2013) · Cochrane | RR 1.4 [1.06, 1.85] | 4 studies · 140 participants | Low |
G‐CSF + standard treatment vs usual treatment Need for surgery: Overall Surgical Interventions · patients with diabetic foot infection Granulocyte‐colony stimulating factors as adjunctive therapy for diabetic foot infections (2013) · Cochrane | RR 0.37 [0.2, 0.68] | 5 studies · 167 participants | Low |
G‐CSF + standard treatment vs usual treatment Need for surgery: Amputation · patients with diabetic foot infection Granulocyte‐colony stimulating factors as adjunctive therapy for diabetic foot infections (2013) · Cochrane | RR 0.41 [0.18, 0.95] | 5 studies · 167 participants | Low |