Number experiencing adverse effects · children with cystic fibrosis and a new culture positive for P aeruginosa
Inhaled tobramycin (TNS) plus oral azithromycin showed no clear difference in adverse effects of antibiotics: number of participants experiencing… compared with TNS plus oral placebo (moderate certainty).
1 finding from 1 review
End‐product score Modified Welling scale · surgical trainees
1 finding from 1 review
Maternal mortality ‐ not reported · women with postpartum iron deficiency anaemia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Fatigue ‐ not reported · women with postpartum iron deficiency anaemia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Persistent anaemia symptoms ‐ not reported · women with postpartum iron deficiency anaemia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Thromboembolic events ‐ not reported · women with postpartum iron deficiency anaemia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Requirement for additional (surgical) interventions (plate removal within 90 days) · Adults with fractures of the mandibular angle
Transbuccal miniplate combined with intraoral approach led to lower requirement for additional (surgical) interventions (plate removal… compared with intraoral approach alone; GRADE not reported.
1 finding from 1 review
Non-union · Adults with fractures of the mandibular angle
Transbuccal miniplate combined with intraoral approach showed no clear difference in non-union compared with intraoral approach alone; GRADE not reported.
1 finding from 1 review
Restoration of function (malocclusion; interincisor mouth opening) · Adults with fractures of the mandibular angle
1 finding from 1 review
Post-operative infection (persistent) · Adults with fractures of the mandibular angle
Transbuccal miniplate combined with intraoral approach showed no clear difference in post-operative infection (persistent) compared with intraoral approach alone; GRADE not reported.
1 finding from 1 review
Facial appearance (scar) · Adults with fractures of the mandibular angle
1 finding from 1 review
Development of any (cavitated or non-cavitated) carious lesion · Children younger than 6 years with caries-free primary dentition (no cavitated or non-cavitated lesions at baseline)
Preschool children with mutans streptococci at baseline probably have about four times higher odds of developing early childhood caries (OR 4.13; moderate certainty).
10 findings from 1 review
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis. 2023 All outcomes6 months to 3.5 years · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Overall
OR 4.13 [3.33, 5.12]
12 studies · 3010 participants
Moderate
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis. 2023 All outcomes6 months to 3.5 years · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Sample: plaque
OR 5.16 [2.99, 8.91]
5 studies · 736 participants
GRADE not reported
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis. 2023 All outcomes6 months to 3.5 years · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Sample: saliva
OR 3.92 [3.20, 4.80]
9 studies · 2577 participants
GRADE not reported
Show 7 more findings
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis. 2023 All outcomes1 year · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Follow-up: 1 year
OR 4.37 [3.50, 5.45]
4 studies · 2016 participants
GRADE not reported
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis. 2023 All outcomes2.7 years (31 months median) · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Follow-up: 2.7 years (31 months median)
OR 33.00 [3.18, 342.26]
1 study · 28 participants
GRADE not reported
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis. 2023 All outcomes2 years · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Follow-up: 2 years
OR 2.53 [1.22, 5.23]
4 studies · 297 participants
GRADE not reported
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis. 2023 All outcomes6 months to 3.5 years · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Microbiological assessment: quantitative (culture/CFU counting)
OR 3.82 [2.01, 7.26]
6 studies · 732 participants
GRADE not reported
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis. 2023 All outcomes3.5 years (42 months) · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Follow-up: 3.5 years (42 months)
OR 4.23 [2.49, 7.18]
1 study · 366 participants
GRADE not reported
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis. 2023 All outcomes6 months · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Follow-up: 6 months
OR 4.65 [2.01, 10.76]
2 studies · 303 participants
GRADE not reported
Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis. 2023 All outcomes6 months to 3.5 years · Caries-free preschool children (<6 y), primary dentition; community/clinic; studies from Japan, Finland, USA, Sweden and Singapore · Microbiological assessment: semi-quantitative (Dentocult/commercial kit)
OR 4.36 [3.53, 5.39]
6 studies · 2278 participants
GRADE not reported
Future caries experience (dmft/dmfs) · Children younger than 6 years with caries-free primary dentition (no cavitated or non-cavitated lesions at baseline)
Children with mutans streptococci at baseline had a greater future caries experience (SMD 0.85, a large effect; ungraded).
1 finding from 1 review
new root-surface carious lesions or restorations · community-dwelling older adults with root caries
SDF plus potassium iodide had a 52% preventative fraction; no pooled estimate or GRADE rating was reported.
1 finding from 1 review
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months) · benzydamine hydrochloride
SoF9 Topical treatments vs placebo. Symptom relief short-term: insufficient or contradictory evidence regarding benefit of any evaluated topical treatment; 150 participants (4 RCTs); very low. Subgroups: benzydamine (1…
4 studies · 150 participants
Very low
Adverse effects · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether topical treatments (lactoperoxidase oral rinse / Biotene) changes relief of burning/discomfort (symptom relief; pain intensity) compared with placebo (very low certainty).
1 finding from 1 review
Maternal mortality ‐ not reported · women with postpartum iron deficiency anaemia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Fatigue ‐ not reported · women with postpartum iron deficiency anaemia
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Persistent anaemia symptoms Reported by the women · women with postpartum iron deficiency anaemia
1 finding from 1 review
no estimate extracted
1 study · 1 participants
GRADE not reported