Question · asked by 1 review

Topical treatments (benzydamine hydrochloride oral rinse) vs placebo: Adverse effects

Population
People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
Intervention
Topical treatments (benzydamine hydrochloride oral rinse)
Comparison
placebo
Outcome
Adverse effects

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Topical treatments (benzydamine hydrochloride oral rinse) vs Placebo
Adverse effects · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such… · short-term (up to 3 months), benzydamine hydrochloride
Interventions for treating burning mouth syndrome (2016) · Cochrane All outcomes
SoF9. Adverse effects: single study narratively reported that no adverse effects occurred from benzydamine hydrochloride oral rinse; 20 participants (1 RCT); very low.1 study · 20 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating burning mouth syndrome
2016 · Cochrane All outcomes
2015-12Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.