Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,645 questions in 107 reviews · Wounds

current versions
No studies 651 · 39.6%Ungraded 84 · 5.1%Very low 554 · 33.7%Low 283 · 17.2%Moderate 64 · 3.9%High 9 · 0.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Alginate dressing (Sorbsan®) vs alternative alginate dressing (Tegagen™ High Gelling)
Health‐related quality of life · people with venous leg ulceration
Alginate dressings for venous leg ulcers (2015) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Alginate dressing vs hydrocolloid dressing
Time to healing · people with venous leg ulceration
Alginate dressings for venous leg ulcers (2015) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Alginate dressing vs hydrocolloid dressing
Proportion of participants with healed ulcers at 6 weeks · people with venous leg ulceration
Alginate dressings for venous leg ulcers (2015) · Cochrane
RR 0.42 [0.14, 1.21]2 studies · 84 participantsVery low
Alginate dressing vs hydrocolloid dressing
Proportion of participants with healed ulcers at 12 weeks · people with venous leg ulceration
Alginate dressings for venous leg ulcers (2015) · Cochrane
RR 1.02 [0.57, 1.81]1 study · 131 participantsVery low
Alginate dressing vs hydrocolloid dressing
Mean change in wound size, with adjustment for baseline size · people with venous leg ulceration
Alginate dressings for venous leg ulcers (2015) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Early dressing removal vs delayed dressing removal
Superficial surgical site infection Superficial surgical site infection within 30 days of surgery · people with surgical site infection
Early versus delayed dressing removal after primary closure of clean and clean‐contaminated surgical wounds (2015) · Cochrane
RR 0.64 [0.32, 1.28]3 studies · 280 participantsVery low
Early dressing removal vs delayed dressing removal
Superficial wound dehiscence Superficial wound dehiscence reported within 30 days of surgery · people with surgical site infection
Early versus delayed dressing removal after primary closure of clean and clean‐contaminated surgical wounds (2015) · Cochrane
RR 2 [0.19, 21.16]2 studies · 180 participantsVery low
Early dressing removal vs delayed dressing removal
Serious adverse events Patients experiencing serious adverse events within 30 days of surgery · people with surgical site infection
Early versus delayed dressing removal after primary closure of clean and clean‐contaminated surgical wounds (2015) · Cochrane
RR 0.83 [0.28, 2.51]1 study · 78 participantsVery low
Early dressing removal vs delayed dressing removal
Length of hospital stay Total length of hospital stay at maximal · people with surgical site infection
Early versus delayed dressing removal after primary closure of clean and clean‐contaminated surgical wounds (2015) · Cochrane
no estimate extracted1 study · 102 participantsLow
Early dressing removal vs delayed dressing removal
Costs Costs at maximal · people with surgical site infection
Early versus delayed dressing removal after primary closure of clean and clean‐contaminated surgical wounds (2015) · Cochrane
no estimate extracted1 study · 102 participantsLow
Intervention NR
Surgical site infection · patients undergoing orthognathic surgery
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery (2015) · Cochrane
RR 0.42 [0.24, 0.74]7 studies · 472 participantsModerate
Intervention NR
Health‐related quality of life · patients undergoing orthognathic surgery
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Systemic infection · patients undergoing orthognathic surgery
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse events · patients undergoing orthognathic surgery
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Duration of hospital stay · patients undergoing orthognathic surgery
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Health‐related quality of life · patients undergoing orthognathic surgery
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Surgical site infection · patients undergoing orthognathic surgery
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery (2015) · Cochrane
RR 0.34 [0.09, 1.22]2 studies · 220 participantsLow
Intervention NR
Adverse events · patients undergoing orthognathic surgery
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery (2015) · Cochrane
no estimate extracted1 study · 70 participantsLow
Intervention NR
Systemic infection · patients undergoing orthognathic surgery
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery (2015) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Duration of hospital stay · patients undergoing orthognathic surgery
Antibiotic prophylaxis for preventing infectious complications in orthognathic surgery (2015) · Cochrane
no estimate extractedNRNo studies
Gauze and tape vs standard polyurethane (SPU)
Catheter‐related blood stream infection · patients with CVC
Dressings and securement devices for central venous catheters (CVC) (2015) · Cochrane
RR 0.64 [0.26, 1.63]8 studies · 506 participantsLow
Gauze and tape vs standard polyurethane (SPU)
Catheter tip colonisation · patients with CVC
Dressings and securement devices for central venous catheters (CVC) (2015) · Cochrane
RR 0.95 [0.51, 1.77]5 studies · 342 participantsVery low
Chlorhexidine gluconate‐impregnated (CGI) dressing vs SPU dressings
Catheter‐related blood stream infection · patients with CVCs
Dressings and securement devices for central venous catheters (CVC) (2015) · Cochrane
RR 0.65 [0.4, 1.05]5 studies · 4876 participantsModerate
Chlorhexidine gluconate‐impregnated (CGI) dressing vs SPU dressings
Catheter tip colonisation: · patients with CVCs
Dressings and securement devices for central venous catheters (CVC) (2015) · Cochrane
RR 0.58 [0.47, 0.73]6 studies · 4431 participantsModerate
Medication‐impregnated dressings vs all other dressing types
Catheter‐related blood stream infection · patients with CVCs
Dressings and securement devices for central venous catheters (CVC) (2015) · Cochrane
RR 0.6 [0.39, 0.93]6 studies · 5687 participantsHigh
Summary of findings. Additional Chinese herbs vs no additional Chinese herbs
Cure rate · patients with gas gangrene
Interventions for treating gas gangrene (2015) · Cochrane
RR 3.08 [1, 9.46]1 study · 46 participantsVery low
Summary of findings. Additional topical HBOT vs additional systemic HBOT
Cure rate · patients with gas gangrene
Interventions for treating gas gangrene (2015) · Cochrane
RR 1.1 [0.25, 4.84]1 study · 44 participantsVery low
Intervention NR
PVC failure · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
no estimate extractedNRNo studies
Transparent dressing vs sticking plaster
PVC failure · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
no estimate extractedNRNo studies
Transparent dressing vs sticking plaster
Dislodgement/accidental removal Observation · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
RR 1.34 [0.72, 2.47]1 study · 703 participantsVery low
Transparent dressing vs sticking plaster
Phlebitis Observation · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
RR 0.89 [0.53, 1.49]1 study · 703 participantsLow
Intervention NR
Dislodgement/accidental removal · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
RR 0.4 [0.17, 0.92]2 studies · 278 participantsVery low
Intervention NR
Phlebitis · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
RR 0.89 [0.47, 1.68]3 studies · 379 participantsVery low
Bordered transparent dressing vs securement device
PVC failure Observation · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
RR 0.86 [0.64, 1.16]1 study · 302 participantsVery low
Bordered transparent dressing vs securement device
Dislodgement/accidental removal Observation · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
RR 0.14 [0.03, 0.63]1 study · 302 participantsVery low
Bordered transparent dressing vs securement device
Phlebitis Observation · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
RR 8.11 [1.03, 64.02]1 study · 302 participantsVery low
Bordered transparent dressing vs tape
PVC failure Observation · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
RR 1.84 [1.09, 3.11]1 study · 153 participantsVery low
Bordered transparent dressing vs tape
Dislodgement/accidental removal Observation · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
RR 1.46 [0.51, 4.14]1 study · 153 participantsVery low
Bordered transparent dressing vs tape
Phlebitis · Patients requiring a peripheral venous catheter
Devices and dressings to secure peripheral venous catheters to prevent complications (2015) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressings vs basic wound contact dressings
Proportion of ulcers completely healed · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
RR 0.97 [0.56, 1.68]1 study · 30 participantsVery low
Hydrogel dressings vs foam dressing
Adverse events (not reported) · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressings vs dextranomer paste dressings
Proportion of ulcers completely healed (not reported) · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressings vs dextranomer paste dressings
Adverse event data · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
no estimate extracted1 study · 135 participantsUngraded
Hydrogel dressings vs collagenase
Proportion of ulcers completely healed · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
no estimate extracted1 study · 27 participantsUngraded
Hydrogel dressings vs collagenase
Adverse events (not reported) · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressings vs basic wound contact dressings
Adverse event data (wound infection and pain during treatment) · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
no estimate extracted0 studies · 3 participantsUngraded
Hydrogel dressings vs hydrocolloid dressings
Proportion of ulcers completely healed · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
RR 1 [0.22, 4.56]1 study · 10 participantsLow
Hydrogel dressings vs hydrocolloid dressings
Adverse events · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
no estimate extracted1 study · 10 participantsUngraded
Hydrogel dressings vs hydrogel dressings
Proportion of ulcers completely healed (not reported) · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
no estimate extractedNRNo studies
Hydrogel dressings vs hydrogel dressings
Adverse events (wound infection) · people with pressure ulcers
Hydrogel dressings for treating pressure ulcers (2015) · Cochrane
RR 0.13 [0.01, 2.44]1 study · 50 participantsLow