Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,509 questions · 2,666 findings · 288 reviews

No studies found 743 · 27.9%GRADE not reported 327 · 12.3%Very low 775 · 29.1%Low 484 · 18.2%Moderate 279 · 10.5%High 58 · 2.2%

Intervention not reported

Perioperative bleeding requiring non‐surgical intervention · patients with paediatric tonsillectomy

The intervention showed no clear difference in perioperative bleeding requiring non‐surgical intervention (moderate certainty).

1 finding from 1 review

Infraclavicular block vs all other brachial plexus blocks

Adequate surgical anaesthesia ‐ At 30 minutes post‐block assessment interval · patients with regional anaesthesia of the lower arm

infraclavicular block showed no clear difference in adequate surgical anaesthesia ‐ At 30 minutes post‐block assessment… compared with all other brachial plexus blocks (high certainty).

1 finding from 1 review

Infraclavicular block vs all other brachial plexus blocks

Supplementation required for surgical anaesthesia · patients with regional anaesthesia of the lower arm

infraclavicular block showed no clear difference in supplementation required to achieve adequate surgical anaesthesia compared with all other brachial plexus blocks (high certainty).

1 finding from 1 review

Intervention not reported

Surgical failure (intraocular pressure >21mmHg) ( · patients with glaucoma surgery

The intervention probably leads to lower surgical failure (intraocular pressure >21mmHg) ( (moderate certainty).

1 finding from 1 review

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Treatment / surgical procedure time · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) with barrier membrane (resorbable… showed no clear difference in treatment / surgical procedure time compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Hard tissue probing at surgical re-entry (bone gain) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher hard tissue probing at surgical re-entry (bone gain) compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

GTR rm associated with bone substitutes vs Open flap debridement (access flap surgery)

Hard tissue probing at surgical re-entry (bone gain) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…

Guided tissue regeneration (GTR) combined with bone substitutes/graft led to higher hard tissue probing at surgical re-entry (bone gain) compared with open flap debridement (access flap surgery); GRADE not reported.

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

All‐cause mortality · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in all‐cause mortality compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Stroke · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in stroke compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Patient readmissions · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in rehospitalisation compared with surgical aortic valve replacement (low certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Myocardial infarction · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in myocardial infarction compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Cardiac mortality · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation showed no clear difference in cardiac death compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review

Transcatheter aortic valve implantation vs surgical aortic valve replacement

Permanent pacemaker implantation · adults with severe aortic stenosis who are at a low surgical risk.

Transcatheter aortic valve implantation probably leads to higher permanent pacemaker implantation compared with surgical aortic valve replacement (moderate certainty).

1 finding from 1 review