Adverse effects of antibiotics: participants experiencing cough · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
It is very uncertain whether inhaled tobramycin (TNS) changes adverse effects of antibiotics: participants experiencing cough compared with placebo (very low certainty).
1 finding from 1 review
Adverse effects of antibiotics · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Intravenous ceftazidime with tobramycin probably leads to lower adverse effects of antibiotics: compared with oral ciprofloxacin (moderate certainty).
1 finding from 1 review
IV antibiotics: number of days on IV antibiotics · adolescents and adults with cystic fibrosis
Digital technology showed no clear difference in IV antibiotics: number of days on IV antibiotics compared with usual care (low certainty).
1 finding from 1 review
Need for antibiotics · children aged up to 16 years with ARTIs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for antibiotics · children aged up to 16 years with ARTIs
Homeopathic medicinal products (individualised treatment) showed no clear difference in need for antibiotics compared with placebo or usual care (low certainty).
1 finding from 1 review
Need for antibiotics · children aged up to 16 years with ARTIs
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants who used prescribed antibiotics for acute URTIs · children, adults, and the elderly
Intention‐to‐treat analysis: probiotics probably leads to lower number of participants who used prescribed antibiotics for acute URTIs compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Need for extra antibiotics (days) · children and young adults with CF
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for extra antibiotics (days) · adults and children with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for extra antibiotics (days) · adolescents and adults with cystic fibrosis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants requiring antibiotics · adults with chronic bronchitis or chronic obstructive pulmonary disease
Summary of findings table ‐ immunostimulant probably leads to lower number of participants requiring antibiotics compared with placebo (moderate certainty).
1 finding from 1 review
Number of exacerbations(as reported by number of hospitalisations and number of courses and days on antibiotics) · adults and children with cystic fibrosis
It is very uncertain whether short‐acting inhaled beta‐2 agonists changes number of exacerbations(as reported by number of hospitalisations… compared with placebo (very low certainty).
1 finding from 1 review
Need for antibiotics · management of retained placenta
It is very uncertain whether oxytocin solution changes need for treatment with antibiotics (infection) compared with expectant management (very low certainty).
1 finding from 1 review
Need for antibiotics · management of retained placenta
Oxytocin solution showed no clear difference in need for treatment with antibiotics (infection) compared with saline solution (moderate certainty).
1 finding from 1 review
Need for antibiotics · management of retained placenta
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for antibiotics · management of retained placenta
It is very uncertain whether saline solution changes need for treatment with antibiotics (infection) compared with expectant management (very low certainty).
1 finding from 1 review
Time to next course of antibiotics  · adults and children with cystic fibrosis
The review found no eligible studies for this question.
2 findings from 1 review
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Duration of time requiring intravenous antibiotics · patients age 10 years and older with periorbital or orbital cellulitis
It is very uncertain whether standard treatment plus systemic corticosteroids changes duration of time requiring intravenous antibiotics compared with standard treatment alone (very low certainty).
1 finding from 1 review
Need for antibiotics days of antibiotic use · children aged over eight and adults with cystic fibrosis and chronic pulmonary infection with P aeruginosa
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Need for antibiotics time to need for antibiotics · children (12 or over) and adults with cystic fibrosis and lung infection
Summary of findings: monoclonal antibody KB001‐A showed no clear difference in need for antibiotics time to need for antibiotics compared with placebo (moderate certainty).
1 finding from 1 review