Cochrane · systematic review · CD014606
Digital technology for early identification of exacerbations in people with cystic fibrosis
Wong, C-H, Smith, S, Kansra, S · Cochrane Database of Systematic Reviews · 2023 · Cochrane Library
Cystic Fibrosis and Genetic DisordersAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 6 · 85.7%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Digital technology versus usual care for early identification of exacerbations in people with cystic fibrosis
Population: adolescents and adults with cystic fibrosis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Time to next pulmonary exacerbation Digital technology vs usual care | HR 1.45 | 2 studies · 153 participants | Moderate Downgraded: risk of bias |
Number of pulmonary exacerbations: number of participants experiencing an exacerbation Digital technology vs usual care | RR 1.07 [0.92, 1.25] | 1 study · 267 participants | Moderate Downgraded: risk of bias |
QoL: change from baseline in CFQ‐R score Digital technology vs usual care | no estimate extracted | 1 study · 60 participants | Moderate Downgraded: imprecision |
FEV1: change from baseline in FEV1 % predicted Digital technology vs usual care | no estimate extracted | 3 studies · 415 participants | Moderate Downgraded: risk of bias |
IV antibiotics: number of days on IV antibiotics Digital technology vs usual care | MD 3.07 | 2 studies · 148 participants | Low Downgraded: risk of bias, inconsistency |
New micro‐organisms: number of participants in whom new organisms are detected Digital technology vs usual care | no estimate extracted | 1 study · 267 participants | Moderate Downgraded: risk of bias |
Adverse events: number of treatment related adverse events Digital technology vs usual care | no estimate extracted | 2 studies · 355 participants | Moderate Downgraded: risk of bias |