Childhood/adulthood type 2 diabetes mellitus · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus
1 finding from 1 review
Neurosensory disability · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus
1 finding from 1 review
Mortality: lung cancer · Patients with lung cancer
Annual chest x‐ray screening showed no clear difference in lung cancer mortality at 6 years of compared with usual care (no regular screening) (high certainty).
2 findings from 1 review
Deaths from all causes (excluding deaths from PLCO cancers) · Patients with lung cancer
Annual chest x‐ray screening showed no clear difference in deaths from all causes (excluding deaths from PLCO cancers) compared with usual care (no regular screening) (high certainty).
1 finding from 1 review
Preterm birth · pregnant women presenting for routine prenatal care
Lower genital tract infection screening probably leads to lower preterm birth less than 37 weeks compared with no screening (moderate certainty).
1 finding from 1 review
Preterm low birthweight (below or equal 2500 g) · pregnant women presenting for routine prenatal care
Lower genital tract infection screening probably leads to lower preterm low birthweight (below or equal 2500 g) compared with no screening (moderate certainty).
1 finding from 1 review
Preterm very low birthweight (below or equal 1500 g) · pregnant women presenting for routine prenatal care
Lower genital tract infection screening probably leads to lower preterm very low birthweight (below or equal 1500 g) compared with no screening (moderate certainty).
1 finding from 1 review
Mortality: lung cancer · healthy adults
Low‐dose computed tomography (LDCT) screening probably leads to lower lung cancer‐related mortality ‐ planned time points compared with no LDCT screening (moderate certainty).
1 finding from 1 review
All‐cause mortality ‐ planned time points · healthy adults
Low‐dose computed tomography (LDCT) screening probably leads to lower all‐cause mortality ‐ planned time points compared with no LDCT screening (moderate certainty).
1 finding from 1 review
Overdiagnosis Time point: ≥ 10 years from randomisation excluding CXR trials  · healthy adults
Low‐dose computed tomography (LDCT) screening showed no clear difference in overdiagnosis Time point: ≥ 10 years from randomisation excluding… compared with no LDCT screening (low certainty).
1 finding from 1 review
Number of invasive tests Time point: 3 years to 10 years from randomisation  · healthy adults
1 finding from 1 review
Any death postsurgery Time point: 6 years to 9 years from randomisation · healthy adults
Low‐dose computed tomography (LDCT) screening showed no clear difference in any death postsurgery Time point: 6 years to 9 years from… compared with no LDCT screening (moderate certainty).
1 finding from 1 review
Health‐related quality of life ‐ anxiety Time point: 10 months to 5 years from randomisation Measured by different scales · healthy adults
Low‐dose computed tomography (LDCT) screening showed no clear difference in health‐related quality of life ‐ anxiety Time point: 10 months to 5… compared with no LDCT screening (low certainty).
1 finding from 1 review
 · healthy adults
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · general population including those at moderate to high risk of CVD, mean age between 30 and 75
Systematic screening showed no clear difference in all‐cause mortality compared with no/opportunistic screening (low certainty).
1 finding from 1 review
Stroke · general population including those at moderate to high risk of CVD, mean age between 30 and 75
Systematic screening showed no clear difference in stroke (total) compared with no/opportunistic screening (low certainty).
1 finding from 1 review
Total coronary heart disease · general population including those at moderate to high risk of CVD, mean age between 30 and 75
Systematic screening showed no clear difference in coronary heart disease (total) compared with no/opportunistic screening (low certainty).
1 finding from 1 review
Cholesterol mg/dL · general population including those at moderate to high risk of CVD, mean age between 30 and 75
1 finding from 1 review
Systolic blood pressure · general population including those at moderate to high risk of CVD, mean age between 30 and 75
1 finding from 1 review
Diastolic blood pressure · general population including those at moderate to high risk of CVD, mean age between 30 and 75
1 finding from 1 review