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Evidence found and GRADE certainty

317 questions · 322 findings · 62 reviews · Eyes and Vision

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No studies found 94 · 29.2%GRADE not reported 15 · 4.7%Very low 63 · 19.6%Low 91 · 28.3%Moderate 45 · 14%High 14 · 4.3%

Patching vs active observation

Stereoacuity at distance Loss of ≥ 2 octaves near stereoacuity Measured using the Preschool Randot test 3 years after surgery · people with intermittent exotropia, aged less than 11 years

The review found no eligible studies for this question.

1 finding from 1 review

Bilateral lateral rectus recession vs lateral rectus recession and medial rectus resection

Stereoacuity at near Loss of ≥ 2 octaves near stereoacuity, measured using the Preschool Randot test 3 years after surgery · people with intermittent exotropia, aged 3 to < 11 years

Bilateral lateral rectus recession showed no clear difference in stereoacuity at near Loss of ≥ 2 octaves near stereoacuity, measured… compared with unilateral lateral rectus recession with medial rectus resection (low certainty).

1 finding from 1 review

Lateral rectus recession and medial rectus plication vs lateral rectus recession and medial rectus resection

Stereoacuity at distance Loss of ≥ 2 octaves near stereoacuity Measured using the Preschool Randot test 3 years after surgery · people with intermittent exotropia, aged over 6 years

The review found no eligible studies for this question.

1 finding from 1 review

Patching vs active observation

Stereoacuity at near · people with intermittent exotropia, aged less than 11 years

Patching showed no clear difference in stereoacuity at near Measured using the Preschool Randot, Titmus… compared with active observation (low certainty).

1 finding from 1 review

Fornix vs limbal‐based conjunctival trabeculectomy flaps

Mean intraocular pressure · People with glaucoma

Fornix showed no clear difference in mean intraocular pressure compared with limbal‐based conjunctival trabeculectomy flaps (moderate certainty).

2 findings from 1 review

Standard treatment plus systemic corticosteroids vs usual care

Preservation of visual acuity · patients age 10 years and older with periorbital or orbital cellulitis

It is very uncertain whether standard treatment plus systemic corticosteroids changes preservation of visual acuity compared with standard treatment alone (very low certainty).

1 finding from 1 review

Radiotherapy combined with anti‐VEGF vs anti‐VEGF alone

Change in visual acuity (logMAR) ‐ 12 months (negative is better) · people with neovascular AMD

Radiotherapy combined with anti‐VEGF showed no clear difference in change in best corrected visual acuity (logMAR units) Measured using… compared with anti‐VEGF alone (low certainty).

1 finding from 1 review

5000‐centistoke vs 1000‐centistoke

Intraocular pressure (IOP) greater than 21 mmHg · surgery for retinal detachment associated with proliferative vitreoretinopathy

5000‐centistoke showed no clear difference in intraocular pressure (IOP) greater than 21 mmHg at 18 months compared with 1000‐centistoke (low certainty).

1 finding from 1 review