Cochrane · systematic review · CD011347
Binocular versus standard occlusion or blurring treatment for unilateral amblyopia in children aged three to eight years
Tailor, V, Ludden, S, Bossi, M, et al. · Cochrane Database of Systematic Reviews · 2022 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
4
No studies
3
Included studies
NR
No studies 3 · 42.9%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 14.3%Moderate 3 · 42.9%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Binocular iPad treatment compared with occlusion therapy for amblyopia
Population: 5‐ to 8‐year‐old children with amblyopia
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in BCVA amblyopic eye after 16 weeks logMAR (lower logMAR values indicate better visual acuity) Binocular iPad treatment vs occlusion therapy | no estimate extracted | 1 study · 63 participants | Moderate Downgraded: imprecision |
Change in BCVA amblyopic eye after 8 weeks logMAR (lower logMAR values indicate better visual acuity) Binocular iPad treatment vs occlusion therapy | no estimate extracted | 1 study · 62 participants | Moderate Downgraded: imprecision |
Change in distance BCVA in the amblyopic eye 12 months after cessation of treatment Binocular iPad treatment vs occlusion therapy | no estimate extracted | NR | No studies |
Adherence to intervention Proportion of adherence to prescribed intervention across predefined categories Binocular iPad treatment vs occlusion therapy | no estimate extracted | 1 study · 63 participants | Moderate Downgraded: imprecision |
Proportion of participants experiencing an adverse event of permanent diplopia (double vision) Reports of diplopia across all measured time points Binocular iPad treatment vs occlusion therapy | no estimate extracted | 1 study · 63 participants | Low Downgraded: imprecision |
Change in the interocular difference in contrast sensitivity Any validated test, from baseline to 16 (± 2) weeks Binocular iPad treatment vs occlusion therapy | no estimate extracted | NR | No studies |
Measurable change in stereopsis after 8 (± 2) weeks and 16 (± 2) weeks of intervention 'Real change' in stereopsis is defined as a change in stereoacuity of two or more octaves. Binocular iPad treatment vs occlusion therapy | no estimate extracted | NR | No studies |