Cochrane · systematic review · CD006126
Tamponade in surgery for retinal detachment associated with proliferative vitreoretinopathy
Schwartz, SG, Flynn Jr, HW, Wang, X, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
28
current version
GRADE rated
11
No studies
17
Included studies
NR
No studies 17 · 60.7%Ungraded 0 · 0%Very low 0 · 0%Low 11 · 39.3%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Silicone oil compared to sulfur hexafluoride (SF6) for surgery for retinal detachment associated with proliferative vitreoretinopathy
Population: surgery for retinal detachment associated with proliferative vitreoretinopathy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Visual acuity ≥ 5/200 at two years Silicone oil vs sulfur hexafluoride (SF6) | RR 1.57 [0.93, 2.66] | 1 study · 87 participants | Low Downgraded: risk of bias |
Macular attachment at two years Silicone oil vs sulfur hexafluoride (SF6) | RR 1.37 [1.01, 1.86] | 1 study · 87 participants | Low Downgraded: risk of bias |
Retina detachment at two years Silicone oil vs sulfur hexafluoride (SF6) | no estimate extracted | NR | No studies |
Visual acuity worse than 20/200 (regardless of anatomic outcome) at two years Silicone oil vs sulfur hexafluoride (SF6) | no estimate extracted | NR | No studies |
Intraocular pressure greater than 21 mmHg at two years Silicone oil vs sulfur hexafluoride (SF6) | no estimate extracted | NR | No studies |
Visually significant cataract at two years Silicone oil vs sulfur hexafluoride (SF6) | no estimate extracted | NR | No studies |
Quality of life measures at two years evaluated using validated scale as reported by study Silicone oil vs sulfur hexafluoride (SF6) | no estimate extracted | NR | No studies |
Silicone oil compared to perfluropropane (C3F8) for surgery for retinal detachment associated with proliferative vitreoretinopathy
Population: surgery for retinal detachment associated with proliferative vitreoretinopathy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Visual acuity ≥ 5/200 at 3 years Silicone oil vs perfluropropane (C3F8) | RR 0.97 [0.73, 1.31] | 1 study · 264 participants | Low Downgraded: risk of bias |
Macular attachment at 3 years Silicone oil vs perfluropropane (C3F8) | RR 1 [0.86, 1.15] | 1 study · 264 participants | Low Downgraded: risk of bias |
Retina detachment at 3 years Silicone oil vs perfluropropane (C3F8) | no estimate extracted | NR | No studies |
Visual acuity worse than 20/200 (regardless of anatomic outcome) at two years Silicone oil vs perfluropropane (C3F8) | no estimate extracted | NR | No studies |
Intraocular pressure (IOP) greater than 21 mmHg Silicone oil vs perfluropropane (C3F8) | no estimate extracted | NR | No studies |
Visually significant cataract at 3 years Silicone oil vs perfluropropane (C3F8) | no estimate extracted | NR | No studies |
Quality of life measures at 3 years evaluated using validated scale as reported by study Silicone oil vs perfluropropane (C3F8) | no estimate extracted | NR | No studies |
Standard silicone oil compared to heavy silicone oil for surgery for retinal detachment associated with proliferative vitreoretinopathy
Population: surgery for retinal detachment associated with proliferative vitreoretinopathy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in visual acuity (logMAR) at one year Standard silicone oil vs heavy silicone oil | no estimate extracted | 1 study · 93 participants | Low Downgraded: risk of bias |
Macular attachment at one year Standard silicone oil vs heavy silicone oil | no estimate extracted | NR | No studies |
Retinal detachment at one year Standard silicone oil vs heavy silicone oil | RR 0.89 [0.54, 1.48] | 1 study · 186 participants | Low Downgraded: risk of bias |
Visual acuity worse than 20/200 (regardless of anatomic outcome) at one year Standard silicone oil vs heavy silicone oil | no estimate extracted | NR | No studies |
Intraocular pressure (IOP) greater than 21 mmHg at one year Standard silicone oil vs heavy silicone oil | no estimate extracted | NR | No studies |
Visually significant cataract at one year Standard silicone oil vs heavy silicone oil | no estimate extracted | NR | No studies |
Quality of life measures at two years evaluated using validated scale as reported by study at one year Standard silicone oil vs heavy silicone oil | no estimate extracted | NR | No studies |
5000‐centistoke compared to 1000‐centistoke for surgery for retinal detachment associated with proliferative vitreoretinopathy
Population: surgery for retinal detachment associated with proliferative vitreoretinopathy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Change in visual acuity (logMAR) at 18 months 5000‐centistoke vs 1000‐centistoke | no estimate extracted | 1 study · 85 participants | Low Downgraded: risk of bias |
Macular attachment at 18 months 5000‐centistoke vs 1000‐centistoke | no estimate extracted | 1 study · 85 participants | Low Downgraded: risk of bias |
Retina detachment ‐ After removal of silicone oil at 18 months 5000‐centistoke vs 1000‐centistoke | RR 0.36 [0.08, 1.67] | 1 study · 85 participants | Low Downgraded: risk of bias |
Visual acuity worse than 20/200 (regardless of anatomic outcome) at 18 months 5000‐centistoke vs 1000‐centistoke | no estimate extracted | NR | No studies |
Intraocular pressure (IOP) greater than 21 mmHg at 18 months 5000‐centistoke vs 1000‐centistoke | RR 0.9 [0.41, 1.94] | 1 study · 86 participants | Low Downgraded: risk of bias |
Visually significant cataract at 18 months 5000‐centistoke vs 1000‐centistoke | RR 1.3 [0.89, 1.89] | 1 study · 86 participants | Low Downgraded: risk of bias |
Quality of life measures at 18 months evaluated using validated scale as reported by study 5000‐centistoke vs 1000‐centistoke | no estimate extracted | NR | No studies |