Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

78 questions · 83 findings · 13 reviews · Headline outcomes only

No studies found 12 · 14.5%GRADE not reported 1 · 1.2%Very low 23 · 27.7%Low 28 · 33.7%Moderate 15 · 18.1%High 4 · 4.8%

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Bupivicaine plus epinephrine · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in bupivicaine plus epinephrine compared with placebo or no treatment (low certainty).

1 finding from 1 review

Any glucocorticoid vs epinephrine

Change in croup score. · children with croup
4 findings from 1 review
Show 1 more finding

Any glucocorticoid vs epinephrine

Return visits or (re)admissions or both · children with croup

Any glucocorticoid showed no clear difference in return visits or (re)admissions or both compared with epinephrine (low certainty).

1 finding from 1 review

Dopamine vs norepinephrine

Total mortalitya · hypotensive shock

Dopamine showed no clear difference in total mortalitya compared with norepinephrine (high certainty).

1 finding from 1 review

Terlipressin vs norepinephrine

Total mortalitya · hypotensive shock

It is very uncertain whether terlipressin changes total mortalitya compared with norepinephrine (very low certainty).

1 finding from 1 review

Vasopressin vs norepinephrine

Total mortalitya · hypotensive shock

Vasopressin showed no clear difference in total mortalitya compared with norepinephrine (moderate certainty).

1 finding from 1 review

Phenylephrine vs norepinephrine

Total mortalitya · hypotensive shock

It is very uncertain whether phenylephrine changes total mortalitya compared with norepinephrine (very low certainty).

1 finding from 1 review

SSRIs or SNRIs vs amitriptyline

Participants who withdraw because of an adverse event or any other reason · patients for whom migraine preventive interventions are indicated

SSRIs or SNRIs showed no clear difference in withdrawn (for any reasons and due to adverse events) compared with amitriptyline (low certainty).

1 finding from 1 review