Cochrane · systematic review · CD003709
Vasopressors for hypotensive shock
Gamper, G, Havel, C, Arrich, J, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 33.3%Low 1 · 16.7%Moderate 1 · 16.7%High 2 · 33.3%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Show all 2 versionsDopamine compared with norepinephrine for hypotensive shock
Population: hypotensive shock
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total mortalitya Dopamine vs norepinephrine | RR 1.07 [0.99, 1.16] | 6 studies · 1400 participants | High |
Arrhythmia < BR/> Dopamine vs norepinephrine | RR 2.33 [1.45, 3.85] | 2 studies · 1931 participants | High |
Terlipressin compared with norepinephrine for hypotensive shock
Population: hypotensive shock
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total mortalitya Terlipressin vs norepinephrine | RR 0.93 [0.69, 1.26] | 7 studies · 231 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Vasopressin compared with norepinephrine for hypotensive shock
Population: hypotensive shock
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total mortalitya Vasopressin vs norepinephrine | RR 0.9 [0.78, 1.03] | 8 studies · 1108 participants | Moderate Downgraded: indirectness |
Phenylephrine compared with norepinephrine for hypotensive shock
Population: hypotensive shock
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total mortalitya Phenylephrine vs norepinephrine | RR 1.08 [0.76, 1.55] | 2 studies · 86 participants | Very low Downgraded: risk of bias, imprecision, indirectness |
Epinephrine compared with norepinephrine for hypotensive shock
Population: hypotensive shock
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Total mortalitya Epinephrine vs norepinephrine | RR 0.88 [0.63, 1.25] | 1 study · 269 participants | Low |