Surgery rate Number requiring emergency surgery · patients with high‐risk bleeding ulcers
Epinephrine probably leads to lower surgery rate Number requiring emergency surgery compared with epinephrine and any second endoscopic method (moderate certainty).
1 finding from 1 review
Surgical field bleeding score (during surgery or < 30 minutes after surgery) · adults and children with chronic rhinosinusitis with or without nasal polyps
1 finding from 1 review
Intraoperative blood loss (mL) · adults and children with chronic rhinosinusitis with or without nasal polyps
1 finding from 1 review
Significant adverse events (seizures, thromboembolism) within 24 hours of surgery) · adults and children with chronic rhinosinusitis with or without nasal polyps
Tranexamic acid showed no clear difference in significant adverse events (seizures, thromboembolism) within 24… compared with placebo (saline solution or sterile water) (moderate certainty).
1 finding from 1 review
Duration of surgery (minutes) Assessed as: total surgical time · adults and children with chronic rhinosinusitis with or without nasal polyps
1 finding from 1 review
Incomplete surgery · adults and children with chronic rhinosinusitis with or without nasal polyps
Tranexamic acid showed no clear difference in incomplete surgery compared with placebo (saline solution or sterile water) (moderate certainty).
1 finding from 1 review
Postoperative bleeding (place of packing or revision surgery within 14 days of surgery) · adults and children with chronic rhinosinusitis with or without nasal polyps
Tranexamic acid showed no clear difference in postoperative bleeding (place of packing or revision surgery within… compared with placebo (saline solution or sterile water) (low certainty).
1 finding from 1 review
Health‐related quality of life (SNOT‐22) (range 0 to 110) · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
1 finding from 1 review
Disease severity, measured by patient‐reported symptom score (VAS) (range 0 to 100) · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
1 finding from 1 review
Significant adverse effects: significant bleeding requiring intervention, severe pain, iatrogenic injury · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adhesion rate · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
Sinonasal debridement may leads to lower adhesion rate compared with no debridement (low certainty).
1 finding from 1 review
Rate of revision surgeries · adult patients who underwent primary endoscopic sinus surgery, with a diagnosis of recurrent acute or chronic rhinosinusitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Endoscopic recurrence · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease
It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes endoscopic recurrence (at week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).
1 finding from 1 review
Conversion to open surgery · with common bile duct stones
LC + LCBDE showed no clear difference in conversion to open surgery compared with LC + post‐operative ERCP (moderate certainty).
1 finding from 1 review
Conversion to open surgery · with common bile duct stones
LC + LCBDE showed no clear difference in conversion to open surgery compared with pre‐operative ERCP + LC (moderate certainty).
1 finding from 1 review
Relief of pain · participants with painful obstructive chronic pancreatitis
Endoscopy probably leads to higher pain relief ‐ middle‐term compared with surgery (moderate certainty).
2 findings from 1 review
Major complications and mortality · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Quality of Life: SF‐36 (physical component) · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Health‐related quality of life (mental) · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Endocrine pancreatic insufficiency (new onset) ‐ long‐term · participants with painful obstructive chronic pancreatitis
Endoscopy showed no clear difference in endocrine pancreatic insufficiency (new onset) ‐ long‐term compared with surgery (low certainty).
1 finding from 1 review