Seizures To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes seizures To discharge compared with opioid alone (very low certainty).
1 finding from 1 review
Mortality after discharge (1‐3 months) · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes mortality post discharge compared with opioid alone (very low certainty).
1 finding from 1 review
Neurodevelopmental disability · newborn infants with opioid withdrawal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · newborn infants with opioid withdrawal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Days' pharmacological treatment · newborn infants with opioid withdrawal
1 finding from 1 review
Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes adverse events (treatment related) To discharge compared with opioid alone (very low certainty).
1 finding from 1 review
Treatment failure To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes treatment failure To discharge compared with phenobarbital and opioid (very low certainty).
1 finding from 1 review
Seizures To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes seizures To discharge compared with phenobarbital and opioid (very low certainty).
1 finding from 1 review
Mortality before hospital discharge · newborn infants with opioid withdrawal
1 finding from 1 review
Neurodevelopmental disability · newborn infants with opioid withdrawal
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · newborn infants with opioid withdrawal
1 finding from 1 review
Days' pharmacological treatment · newborn infants with opioid withdrawal
1 finding from 1 review
Adverse events (treatment related) To discharge · newborn infants with opioid withdrawal
It is very uncertain whether clonidine and opioid changes adverse events (treatment related) To discharge compared with phenobarbital and opioid (very low certainty).
1 finding from 1 review
Completion of treatment · management of opium withdrawal
It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: baclofen versus clonidine compared with other pharmacological detoxification treatment (very low certainty).
2 findings from 1 review
RR 1.06 [0.63, 1.8]
66 participants
Very low
RR 2.01 [1.69, 2.38]
361 participants
Low
Completion of treatment: clonidine versus clonidine plus amantadine, inpatient setting · management of opium withdrawal
It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus clonidine plus amantadine,… compared with other pharmacological detoxification treatment (very low certainty).
1 finding from 1 review
RR 1.03 [0.86, 1.24]
69 participants
Very low
Completion of treatment: clonidine versus buprenorphine, inpatient setting · management of opium withdrawal
It is very uncertain whether pharmacological detoxification treatment changes completion of treatment: clonidine versus buprenorphine, inpatient… compared with other pharmacological detoxification treatment (very low certainty).
1 finding from 1 review
RR 1.04 [0.9, 1.2]
35 participants
Very low
Withdrawal symptoms · management of opium withdrawal
2 findings from 1 review
no estimate extracted
60 participants
Very low
no estimate extracted
34 participants
Very low
Intervention not reported
LASB (lidocaine + clonidine) vs IVRB (lidocaine + clonidine) · adults with CRPS
1 finding from 1 review
Emergence agitation—Clonidine · patients with emergence agitation
Other GA/adjunct leads to lower emergence agitation—Clonidine compared with sevoflurane anaesthesia (high certainty).
1 finding from 1 review
Intervention not reported
Number commencing naltrexone maintenance treatment ‐ Clonidine comparison · patients with opioid withdrawal
The intervention probably leads to higher number commencing naltrexone maintenance treatment ‐ Clonidine… (moderate certainty).
1 finding from 1 review