Cochrane · systematic review · CD007084
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children
Costi, D, Cyna, AM, Ahmed, S, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
AnaesthesiaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 28.6%High 5 · 71.4%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Other GA/adjunct versus sevoflurane anaesthesia for reducing risk of emergence agitation
Population: patients with emergence agitation
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Emergence agitation—Propofol induction and maintenance Other GA/adjunct vs sevoflurane anaesthesia | RR 0.35 [0.25, 0.51] | 14 studies · 1098 participants | High |
Emergence agitation—Dexmedetomidine Other GA/adjunct vs sevoflurane anaesthesia | RR 0.37 [0.29, 0.47] | 12 studies · 851 participants | High |
Emergence agitation—Fentanyl Other GA/adjunct vs sevoflurane anaesthesia | RR 0.37 [0.27, 0.5] | 15 studies · 1247 participants | High |
Emergence agitation—Clonidine Other GA/adjunct vs sevoflurane anaesthesia | RR 0.45 [0.31, 0.66] | 9 studies · 739 participants | High |
Emergence agitation—Halothane Other GA/adjunct vs sevoflurane anaesthesia | RR 0.51 [0.41, 0.63] | 34 studies · 3534 participants | High |
Emergence agitation—Isoflurane Other GA/adjunct vs sevoflurane anaesthesia | RR 0.76 [0.46, 1.23] | 6 studies · 379 participants | Moderate Downgraded: imprecision |
Emergence agitation—Desflurane Other GA/adjunct vs sevoflurane anaesthesia | RR 1.46 [0.92, 2.31] | 6 studies · 408 participants | Moderate Downgraded: imprecision |