Non‐cessation of seizures · patients with status epilepticus
Lorazepam IV showed no clear difference in non‐cessation of seizures compared with diazepam plus phenytoin IV (low certainty).
1 finding from 1 review
Adverse effects · patients with status epilepticus
Lorazepam IV showed no clear difference in adverse effects compared with diazepam plus phenytoin IV (moderate certainty).
1 finding from 1 review
Deaths · patients with status epilepticus
1 finding from 1 review
Requirement for ventilatory support · patients with status epilepticus
1 finding from 1 review
At least 50% reduction in pain · patients with fibromyalgia
Pregabalin leads to higher 50% pain reduction compared with placebo at end of treatment (high certainty).
1 finding from 1 review
Patient Global Impression of Change much or very much improved · patients with fibromyalgia
Pregabalin leads to higher patient Global Impression of Change of 'much' or 'very much' improved compared with placebo at end of treatment (high certainty).
1 finding from 1 review
Fatigue · patients with fibromyalgia
1 finding from 1 review
Participant‐reported sleep problems (scale: 0 to 28; higher scores indicate more sleep problems) · patients with fibromyalgia
1 finding from 1 review
Withdrawals due to adverse events · patients with fibromyalgia
Pregabalin leads to higher withdrawal due to adverse events compared with placebo at end of treatment (high certainty).
1 finding from 1 review
Serious adverse events · patients with fibromyalgia
Pregabalin showed no clear difference in serious adverse events compared with placebo at end of treatment (moderate certainty).
1 finding from 1 review
Dizziness · patients with fibromyalgia
Pregabalin leads to higher dizziness reported to be an adverse event compared with placebo at end of treatment (high certainty).
1 finding from 1 review