Pregabalin vs placebo at end of treatment: Patient Global Impression of Change much or very much improved
- Population
- patients with fibromyalgia
- Intervention
- Pregabalin
- Comparison
- placebo at end of treatment
- Outcome
- Patient Global Impression of Change much or very much improved
Pregabalin leads to higher patient Global Impression of Change of 'much' or 'very much' improved compared with placebo at end of treatment (high certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Pregabalin vs placebo at end of treatment Patient Global Impression of Change of 'much' or 'very much' improved · People with fibromyalgia Pregabalin leads to higher patient Global Impression of Change of 'much' or 'very much' improved compared with placebo at end of treatment (high certainty). Anticonvulsants for fibromyalgia (2013) · Cochrane Headline outcomes only | RR 1.38 [1.23, 1.55] | 5 studies · 3183 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Anticonvulsants for fibromyalgia 2013 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.