Summary of findings ‐ Intravenous lorazepam vs intravenous diazepam/intravenous phenytoin combination: Non‐cessation of seizures
Lorazepam IV showed no clear difference in non‐cessation of seizures compared with diazepam plus phenytoin IV (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Lorazepam IV vs diazepam plus phenytoin IV Non‐cessation of seizures · patients with status epilepticus Lorazepam IV showed no clear difference in non‐cessation of seizures compared with diazepam plus phenytoin IV (low certainty). Anticonvulsant therapy for status epilepticus (2014) · Cochrane Headline outcomes only | no estimate extracted | 2 studies · 370 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Anticonvulsant therapy for status epilepticus 2014 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.