Disease-free survival · Adults with oral cavity cancer
It is very uncertain whether elective radical (comprehensive) neck dissection changes disease-free survival (new disease, progression, and mortality) compared with elective selective neck dissection (very low certainty).
1 finding from 1 review
Adverse effects on oral health: caries (lower arch) · People who had received fixed appliance orthodontic treatment
It is very uncertain whether full-time clear plastic (removable) retainer changes adverse effects on oral health: caries (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).
1 finding from 1 review
Limitation of chewing or swallowing · Adults (>18 years) with established dry socket following permanent tooth extraction
The review found no eligible studies for this question.
1 finding from 1 review
Quality of life · People aged 12 years and over with painful TMD lasting 3 months or longer
The review found no eligible studies for this question.
1 finding from 1 review
Reduction in pain intensity · People aged 12 years and over with painful TMD lasting 3 months or longer
Cognitive behavioural therapy (CBT) showed no clear difference in pain intensity at treatment completion compared with alternative (active) treatment (e.g. oral splint, medication,… (low certainty).
2 findings from 1 review
Post-treatment pain within 1 week (from first session) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment probably leads to higher post-treatment pain within 1 week (from first session) compared with multiple-visit root canal treatment (two or more visits) (moderate certainty).
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
Chlorhexidine (CHX) led to lower reduction in level of contamination by particles >5 um (droplets) at… compared with essential oils/herbal mouthwash; GRADE not reported.
4 findings from 1 review
MD -44.1 [-59.12, -29.08]
1 study · 20 participants
GRADE not reported
Bay 1993 compared 0.12% CHX with essential oil mouthwash C (Listerine) at pharynx level (Andersen's level 2), which was considered patient level and hence was not analysed. No pooled estimate or GRADE rating.
1 study
GRADE not reported
MD -12.21 [-15.58, -8.83]
3 studies · 76 participants
Low
Show 1 more finding
Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
1 finding from 1 review
No adverse events were reported. Six trials (673 participants) reported no adverse events from the use of chlorhexidine gel; one study (Rubio-Palau 2015) reported gastrointestinal discomfort (30, 18%), dizziness (10,…
7 studies
GRADE not reported
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether povidone iodine changes reduction in level of contamination by particles >5 um (droplets) at… compared with ozonated water (very low certainty).
1 finding from 1 review
Time to initial pain relief (minutes) · Adults (>18 years) with established dry socket following permanent tooth extraction
Neocone led to higher time to initial pain relief (minutes) compared with alvogyl; GRADE not reported.
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
It is very uncertain whether chlorhexidine (CHX) changes reduction in level of contamination by particles >5 um (droplets) at… compared with cetylpyridinium chloride (CPC) (very low certainty).
9 findings from 1 review
MD 8.8 [2.7, 14.9]
1 study · 20 participants
Very low
MD 17.4 [11.3, 23.5]
1 study · 20 participants
Very low
MD -11.5 [-18.37, -4.63]
1 study · 20 participants
Very low
Show 6 more findings
MD -8.8 [-14.9, -2.7]
1 study · 20 participants
Very low
MD -2.2 [-9.07, 4.67]
1 study · 20 participants
Very low
MD -30 [-85.86, 25.86]
1 study · 30 participants
Very low
MD -0.2 [-6.3, 5.9]
1 study · 20 participants
Very low
MD 13.6 [6.73, 20.47]
1 study · 20 participants
Very low
MD 4.43 [-2.27, 11.13]
2 studies · 50 participants
Very low
Proportion of children with treated/untreated caries (receipt of dental care) · School children (aged 4 to 15 years), primary and secondary schools in the UK and India
The review found no eligible studies for this question.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Tranexamic acid (AMCA cones) showed no clear difference in presence of dry socket compared with placebo (lactose cones); GRADE not reported.
1 finding from 1 review
Adverse events · Children with caries-free second primary molars, aged 4-8 years (dental clinic, Turkey and Spain)
The review found no eligible studies for this question.
1 finding from 1 review
Attachment change · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…
Full-mouth scaling (FMS): scaling/root planing (subgingival… showed no clear difference in change in clinical attachment level (CAL) compared with quadrant scaling and root planing (control): SRP of each quadrant in… (low certainty).
1 finding from 1 review
Attachment change · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…
Full-mouth scaling (FMS): scaling/root planing (subgingival… showed no clear difference in change in clinical attachment level (CAL) compared with full-mouth disinfection (FMD): scaling/root planing (subgingival… (low certainty).
1 finding from 1 review
Reduction in level of contamination by particles >5 um (droplets) at <2 m from patient's oral cavity · Dental patients undergoing aerosol-generating procedures (AGPs) and the dental healthcare providers treating them
5 findings from 1 review
At operator level, because of high heterogeneity (I2 = 98%), the results were not meta-analysed (6 studies, 196 participants). No pooled estimate or GRADE rating.
6 studies · 196 participants
GRADE not reported
MD -632.94 [-1267.33, 1.45]
3 studies · 80 participants
Very low
MD -101.1 [-107.01, -95.19]
1 study · 20 participants
Low
Show 2 more findings
Bay 1993 compared 0.12% CHX with distilled water (30-second rinse) and evaluated the outcome at patient level (Andersen's level 2, oropharynx); the data were not included in the meta-analysis. No pooled estimate or…
1 study
GRADE not reported
At assistant level, because of high heterogeneity (I2 = 96%), the results were not meta-analysed (4 studies, 136 participants). No pooled estimate or GRADE rating.
4 studies · 136 participants
GRADE not reported
Pocket closure (sites with PPD <=4 mm) · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…
1 finding from 1 review
MRONJ (incidence proportion) · People on antiresorptive treatment undergoing tooth extraction (at risk of MRONJ)
1 finding from 1 review
All participants had complete mucosal coverage without any signs of MRONJ at the final control examination 90 days postoperatively (77 randomised; 1 RCT); no case of postoperative MRONJ in either group; effect not…
1 study · 77 participants
GRADE not reported