Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,908 questions · 3,101 findings · 509 reviews

No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Intervention not reported

Pain intensity (visual analogue score from 0 to 10 where 10 is the most severe pain) · children and young adults with SCD

It is very uncertain whether the intervention changes pain intensity (visual analogue score from 0 to 10 where 10 is the… (very low certainty).

1 finding from 1 review

Guided imagery vs quiet rest

Antihypertensive drug use · pregnant women (between 30 and 36 weeks’ gestation) with elevated blood pressure

Guided imagery showed no clear difference in antihypertensive drug use compared with quiet rest (low certainty).

1 finding from 1 review

Fixed reduction of dialysate temperature vs standard dialysate temperature

Intradialytic hypotension rate · patients requiring haemodialysis

It is very uncertain whether fixed reduction of dialysate temperature changes intradialytic hypotension rate compared with standard dialysate temperature (very low certainty).

1 finding from 1 review

Isothermal dialysate vs thermoneutral dialysate

Intradialytic hypotension rate · patients requiring haemodialysis

It is very uncertain whether isothermal dialysate changes intradialytic hypotension rate compared with thermoneutral dialysate (very low certainty).

1 finding from 1 review

HALOPERIDOL vs placebo

The event rate of intensive care delirium within 28 days. · critically ill patients 18 years or older demanding mechanical ventilation within the first 72 hours (Page 2013) or anticipated needing…

Haloperidol showed no clear difference in the event rate of intensive care delirium within 28 days. compared with placebo (moderate certainty).

1 finding from 1 review