Cochrane · systematic review · CD012762

Transcutaneous electrical nerve stimulation (TENS) for pain management in sickle cell disease

Pal, S, Dixit, R, Moe, S, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library

SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
3
No studies
4
Included studies
NR
No studies 4 · 57.1%Ungraded 0 · 0%Very low 3 · 42.9%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Comparison

Population: children and young adults with SCD
7 questions
OutcomeEffectEvidenceStatus / GRADE
Pain relief (percentage relief compared to baseline)
no estimate extractedNRNo studies
Pain intensity (visual analogue score from 0 to 10 where 10 is the most severe pain)
no estimate extracted1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision
Frequency of pain episodes
no estimate extractedNRNo studies
Change in consumption of analgesics (number of participants requiring analgesia)
no estimate extracted1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision
Change in QoL
no estimate extractedNRNo studies
Change in ability to cope with ADL
no estimate extractedNRNo studies
Adverse effects
no estimate extracted1 study · 22 participantsVery low
Downgraded: risk of bias, imprecision