Cochrane · systematic review · CD012598

Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring haemodialysis

Tsujimoto, Y, Tsujimoto, H, Nakata, Y, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library

Kidney and TransplantAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
12
current version
GRADE rated
3
No studies
6
Included studies
NR
No studies 6 · 50%Ungraded 3 · 25%Very low 3 · 25%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Fixed reduction of dialysate temperature compared to standard dialysate temperature for patients requiring haemodialysis

Population: patients requiring haemodialysis
6 questions
OutcomeEffectEvidenceStatus / GRADE
Intradialytic hypotension rate
Fixed reduction of dialysate temperature vs standard dialysate temperature
RR 0.52 [0.34, 0.8]8 studies · 153 participantsVery low
Downgraded: risk of bias
Discomfort rate
Fixed reduction of dialysate temperature vs standard dialysate temperature
Rate ratio 8.31 [1.86, 37.12]4 studies · 81 participantsVery low
Downgraded: risk of bias
Dropout due to adverse events
Fixed reduction of dialysate temperature vs standard dialysate temperature
no estimate extracted9 studies · 268 participantsUngraded
Death (all causes)
Fixed reduction of dialysate temperature vs standard dialysate temperature
no estimate extractedNRNo studies
Acute coronary syndrome
Fixed reduction of dialysate temperature vs standard dialysate temperature
no estimate extractedNRNo studies
Stroke
Fixed reduction of dialysate temperature vs standard dialysate temperature
no estimate extractedNRNo studies

Isothermal dialysate compared to thermoneutral dialysate in patients requiring haemodialysis

Population: patients requiring haemodialysis
6 questions
OutcomeEffectEvidenceStatus / GRADE
Intradialytic hypotension rate
Isothermal dialysate vs thermoneutral dialysate
Rate ratio 0.68 [0.6, 0.76]2 studies · 133 participantsVery low
Downgraded: risk of bias
Discomfort rate
Isothermal dialysate vs thermoneutral dialysate
no estimate extracted1 study · 17 participantsUngraded
Dropout due to adverse event
Isothermal dialysate vs thermoneutral dialysate
no estimate extracted2 studies · 133 participantsUngraded
Death (all causes)
Isothermal dialysate vs thermoneutral dialysate
no estimate extractedNRNo studies
Acute coronary syndrome
Isothermal dialysate vs thermoneutral dialysate
no estimate extractedNRNo studies
Stroke
Isothermal dialysate vs thermoneutral dialysate
no estimate extractedNRNo studies