Same antimicrobial agent ‐ No cure (good quality studies) · patients with asymptomatic bacteriuria during pregnancy
Single‐dose antibiotic leads to higher same antimicrobial agent ‐ No cure (good quality studies) compared with short‐course (four‐ to seven‐day) antibiotic (high certainty).
1 finding from 1 review
Different antimicrobial agents ‐ No cure (good quality studies) · patients with asymptomatic bacteriuria during pregnancy
Single‐dose antibiotic showed no clear difference in different antimicrobial agents ‐ No cure (good quality studies) compared with short‐course (four‐ to seven‐day) antibiotic (low certainty).
1 finding from 1 review
Antibiotics (systemic) vs No antibiotics, placebo, or a different type of antibiotic
Outcome not reported · Patients (mainly children and young adults) with a history of dental trauma and a diagnosis of luxation (intrusion, extrusion, or lateral…
The review found no eligible studies for this question.
1 finding from 1 review
Late‐onset blood steam infection · newborn infants undergoing removal of central venous catheter
Antibiotics on removal of central venous catheter showed no clear difference in late‐onset blood steam infection compared with no antibiotics (low certainty).
1 finding from 1 review
Neonatal mortality · newborn infants undergoing removal of central venous catheter
1 finding from 1 review
Mortality before hospital discharge · newborn infants undergoing removal of central venous catheter
1 finding from 1 review
Infection‐related mortality before hospital discharge · newborn infants undergoing removal of central venous catheter
1 finding from 1 review
Central line‐associated blood stream infection · newborn infants undergoing removal of central venous catheter
Antibiotics on removal of central venous catheter showed no clear difference in central line‐associated blood stream infection compared with no antibiotics (low certainty).
1 finding from 1 review
Clinical cure · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze
Antibiotic therapy showed no clear difference in clinical cure (symptomatic and clinical recovery by the end of… compared with placebo compared to placebo (moderate certainty).
1 finding from 1 review
Treatment failure (development of more severe signs and symptoms by the end of treatment) · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze
Antibiotic therapy may leads to lower treatment failure (development of more severe signs and symptoms by… compared with placebo compared to placebo (low certainty).
1 finding from 1 review
Relapse · children, aged 2 to 59 months, with WHO‐defined non‐severe pneumonia and wheeze
Antibiotic therapy showed no clear difference in relapse (children who were 'cured' but developed symptoms within… compared with placebo compared to placebo (low certainty).
1 finding from 1 review
FEV1 (% predicted): mean change from baseline · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
1 finding from 1 review
Time to next pulmonary exacerbation · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
1 finding from 1 review
Adverse events (moderate) · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
It is very uncertain whether summary of findings: Inhaled antibiotics plus IV antibiotics changes adverse events moderate adverse events experienced during and after… compared with IV antibiotics only (very low certainty).
1 finding from 1 review
Microbiology Emergence of resistant organisms · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
It is very uncertain whether summary of findings: Inhaled antibiotics plus IV antibiotics changes microbiology Emergence of resistant organisms compared with IV antibiotics only (very low certainty).
1 finding from 1 review
Quality of life: number of participants achieving MCID · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
Summary of findings: Inhaled antibiotics plus IV antibiotics showed no clear difference in quality of life: number of participants achieving MCID compared with IV antibiotics only (low certainty).
1 finding from 1 review
Time off school or work · adults and children with cystic fibrosis (during acute exacerbations of lung disease)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Resolution of ear discharge ‐ measured at 1 to 2 weeks · patients with mucopurulent otorrhoea
It is very uncertain whether topical antibiotics changes resolution of ear discharge ‐ measured at 1 to 2 weeks compared with placebo/no treatment (very low certainty).
1 finding from 1 review
Resolution of ear discharge ‐ measured after 4 weeks · patients with mucopurulent otorrhoea
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life · patients with mucopurulent otorrhoea
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found