Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

864 questions · 895 findings · 140 reviews · Headline outcomes only

No studies found 202 · 22.6%GRADE not reported 53 · 5.9%Very low 227 · 25.4%Low 254 · 28.4%Moderate 131 · 14.6%High 28 · 3.1%

Additional radon in carbon dioxide baths vs carbon dioxide baths only

Improvement More than 1 category change in pain intensity on 4‐point scale (no pain/sporadic/daily/continuous) · patients with rheumatoid arthritis

Additional radon in carbon dioxide baths showed no clear difference in improvement More than 1 category change in pain intensity on 4‐point… compared with carbon dioxide baths only (low certainty).

2 findings from 1 review

Cyanoacrylate vs band ligation

Failure of intervention Continuous variceal bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes failure of intervention Continuous variceal bleeding after… compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Failure of intervention Continuous bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes failure of intervention Continuous bleeding after intervention compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Anticonvulsant vs placebo

Continuous abstinence rate at · patients with alcohol dependence

Anticonvulsants showed no clear difference in continuous abstinence compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Low dose SSRI versus placebo Luteal or continuous administration · women with premenstrual syndrome

The intervention probably leads to higher low dose SSRI versus placebo Luteal or continuous administration (moderate certainty).

1 finding from 1 review

Intervention not reported

Mod dose SSRI versus placebo Luteal or continuous administration · women with premenstrual syndrome

The intervention probably leads to higher mod dose SSRI versus placebo Luteal or continuous administration (moderate certainty).

1 finding from 1 review

Intervention not reported

High dose SSRIs versus placebo Continuous administration · women with premenstrual syndrome

The intervention probably leads to higher high dose SSRIs versus placebo Continuous administration (moderate certainty).

1 finding from 1 review