Cochrane · systematic review · CD010862
Pharmacological interventions for drug‐using offenders
Perry, AE, Neilson, M, Martyn‐St James, M, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Drugs and AlcoholAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
8
current version
GRADE rated
8
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 7 · 87.5%Moderate 1 · 12.5%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings for the main comparisons: Agonist pharmacological compared to no intervention for drug‐using offenders
Population: drug‐using offenders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Drug use (objective) hair and urine analyses Summary of findings for the main comparisons: Agonist pharmacological vs no intervention | RR 0.72 [0.51, 1] | 2 studies · 237 participants | Low Downgraded: risk of bias, inconsistency |
Drug use self reported dichotomous self report information Summary of findings for the main comparisons: Agonist pharmacological vs no intervention | RR 0.61 [0.31, 1.18] | 3 studies · 317 participants | Low Downgraded: inconsistency |
Drug use self reported continuous self report information Summary of findings for the main comparisons: Agonist pharmacological vs no intervention | no estimate extracted | 3 studies · 510 participants | Low Downgraded: risk of bias, inconsistency |
Criminal activity dichotomous ‐ Arrests official records Summary of findings for the main comparisons: Agonist pharmacological vs no intervention | RR 0.6 [0.32, 1.14] | 1 study · 62 participants | Low Downgraded: risk of bias |
Criminal activity dichotomous ‐ Re‐incarceration official records Summary of findings for the main comparisons: Agonist pharmacological vs no intervention | RR 0.77 [0.36, 1.64] | 3 studies · 472 participants | Low Downgraded: risk of bias, inconsistency |
Criminal activity continuous mean number of crime dayes Summary of findings for the main comparisons: Agonist pharmacological vs no intervention | no estimate extracted | 1 study · 51 participants | Low Downgraded: risk of bias |
Summary of findings for the main comparisons: Antagonost (Naltrexone) compared to no pharmacological for drug‐using offenders
Population: patients with drug‐using offenders
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Criminal activity dichotomous ‐ Reincarceration official records Summary of findings for the main comparisons: Antagonost (Naltrexone) vs no pharmacological | RR 0.4 [0.21, 0.74] | 2 studies · 114 participants | Moderate Downgraded: risk of bias |
drug use (objective) urine screen Summary of findings for the main comparisons: Antagonost (Naltrexone) vs no pharmacological | RR 0.69 [0.28, 1.7] | 1 study · 63 participants | Low Downgraded: risk of bias |