Cochrane · systematic review · CD003717
Audio‐visual presentation of information for informed consent for participation in clinical trials
Synnot, A, Ryan, R, Prictor, M, et al. · Cochrane Database of Systematic Reviews · 2014 · Cochrane Library
Consumers and CommunicationAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
23
current version
GRADE rated
13
No studies
10
Included studies
NR
No studies 10 · 43.5%Ungraded 0 · 0%Very low 4 · 17.4%Low 9 · 39.1%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Summary of findings (Comparison 1)
Population: People with a health condition or nominally 'well' considering real clinical trial participation (across a range of topic areas)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Knowledge (Single intervention) [mean number of correct questionnaire responses, assessed immediately post‐intervention] | no estimate extracted | 1 study · 155 participants | Very low Downgraded: risk of bias, imprecision |
Knowledge (Multi‐component intervention) [mean number of correct questionnaire responses, assessed immediately post‐intervention] | no estimate extracted | 1 study · 126 participants | Very low Downgraded: risk of bias, imprecision |
Satisfaction with the information provided (Single and multi‐component intervention) | no estimate extracted | NR | No studies |
Rate of participation (Single intervention) | no estimate extracted | NR | No studies |
Rate of participation (Multiple intervention) [questionnaire, measured immediately post‐intervention] | no estimate extracted | 1 study · 110 participants | Very low Downgraded: risk of bias, imprecision |
Anxiety, or other psychological distress (Single and multi‐component intervention) | no estimate extracted | NR | No studies |
Retention of knowledge (Single and multi‐component intervention) | no estimate extracted | NR | No studies |
Satisfaction with the decision‐making process (single intervention) | no estimate extracted | NR | No studies |
Satisfaction with the decision‐making process (multi‐component intervention) [questionnaire, assessed immediately post‐intervention] | no estimate extracted | 1 study · 126 participants | Very low Downgraded: risk of bias, imprecision |
Summary of findings (Comparison 2)
Population: people with a health condition (or pregnant) considering real clinical trial participation (across a range of topic areas)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Knowledge ‐ continuous [mean number of correct questionnaire responses, measured immediately post‐intervention] | no estimate extracted | 2 studies · 143 participants | Low Downgraded: imprecision, inconsistency |
Knowledge ‐ dichotomous [> 80% of knowledge questions correct, measured immediately post‐intervention] | no estimate extracted | 2 studies · 290 participants | Low Downgraded: imprecision, inconsistency |
Satisfaction with the information provided | no estimate extracted | NR | No studies |
Rate of participation [case notes or questionnaire, measured immediately or up to four weeks post‐intervention] | no estimate extracted | 2 studies · 258 participants | Low Downgraded: imprecision, inconsistency |
Anxiety (or other psychological stress) [Spielberger State and Trait Anxiety score, measured immediately post‐intervention] | no estimate extracted | 1 study · 142 participants | Low Downgraded: imprecision, inconsistency |
Retention of knowledge [> 80% of knowledge questions correct, measured two to four weeks post‐intervention] | RR 1.38 [1.07, 1.77] | 1 study · 85 participants | Low Downgraded: imprecision, inconsistency |
Satisfaction with the decision‐making process | no estimate extracted | NR | No studies |
Summary of findings (Comparison 3)
Population: people with a health condition or nominally 'well' considering real or hypothetical clinical trial participation in cancer or psychiatric medication trials
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Knowledge [questionnaire (scored out of 80), measured immediately post‐intervention] | no estimate extracted | 1 study · 93 participants | Low Downgraded: imprecision |
Knowledge [scored correct answer to single question, measured immediately post‐intervention] | RR 1.17 [0.96, 1.43] | 1 study · 49 participants | Low Downgraded: imprecision |
Satisfaction with the information provided [single question, measured immediately post‐intervention] | RR 3.3 [1.24, 8.78] | 1 study · 44 participants | Low Downgraded: imprecision |
Rate of participation [case notes, measured immediately post‐intervention] | RR 0.41 [0.13, 1.33] | 1 study · 49 participants | Low Downgraded: imprecision |
Anxiety, or other psychological distress | no estimate extracted | NR | No studies |
Retention of knowledge | no estimate extracted | NR | No studies |
Satisfaction with the decision‐making process | no estimate extracted | NR | No studies |