Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

185 questions · 222 findings · 37 reviews · Pain, Palliative and Supportive Care

No studies found 32 · 14.4%GRADE not reported 12 · 5.4%Very low 74 · 33.3%Low 56 · 25.2%Moderate 42 · 18.9%High 6 · 2.7%

CBT vs TAU

Reduction in pain intensity · chronic pain (excluding headache) in adults

It is very uncertain whether CBT changes pain intensity (number of people with ≥ 30 % improvement)… compared with TAU (at follow‐up) (very low certainty).

2 findings from 2 reviews · compare the 2 reviews

Ibuprofen vs morphine

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · children with acute postoperative pain

The review found no eligible studies for this question.

2 findings from 1 review

Ibuprofen vs ketorolac

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · children with acute postoperative pain

The review found no eligible studies for this question.

2 findings from 1 review

Intervention not reported

Pain intensity measured on CHQ (0‐100; 0 = worse pain), and VAS (0 to 100; 0 = no pain) Postintervention: first assessment after end of treatment; no later than 3 months · children and adolescents aged 4 years to 18 years, with chronic musculoskeletal pain
1 finding from 1 review

CBT vs active control

Participant‐reported pain relief of 30% or greater · chronic pain (excluding headache) in adults
2 findings from 1 review

CBT vs active control

Pain intensity (number of people with ≥ 50% improvement) · chronic pain (excluding headache) in adults
2 findings from 1 review