Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

444 questions · 453 findings · 34 reviews · Headline outcomes only

No studies found 117 · 25.8%GRADE not reported 17 · 3.8%Very low 176 · 38.9%Low 96 · 21.2%Moderate 34 · 7.5%High 13 · 2.9%

Malaria rapid diagnostic test (mRDT) vs clinical diagnosis

Antimalarial prescribing to microscopy‐ or PCR‐negative people · people with suspected malaria

Malaria rapid diagnostic test (mRDT) probably leads to lower antimalarial prescribing to microscopy‐ or PCR‐negative people compared with clinical diagnosis (moderate certainty).

1 finding from 1 review

Malaria rapid diagnostic test (mRDT) vs clinical diagnosis

Antibiotic prescribing to microscopy‐ or PCR‐negative people · people with suspected malaria

Malaria rapid diagnostic test (mRDT) probably leads to higher antibiotic prescribing to microscopy‐ or PCR‐negative people compared with clinical diagnosis (moderate certainty).

1 finding from 1 review

Early warning systems (EWS) and rapid response systems (RRS) vs usual care

Hospital mortality – non‐randomised studies ( · adult on acute hospital wards at risk of clinical deterioration
2 findings from 1 review

Early warning systems (EWS) and rapid response systems (RRS) vs usual care

Length of hospital stay · adult on acute hospital wards at risk of clinical deterioration

The review found no eligible studies for this question.

2 findings from 1 review

Early warning systems (EWS) and rapid response systems (RRS) vs usual care

Adverse events (unexpected cardiac or respiratory arrest) – non‐randomised studies ( · adult on acute hospital wards at risk of clinical deterioration
2 findings from 1 review

Early warning systems (EWS) and rapid response systems (RRS) vs usual care

Composite outcome – randomised trials Composite outcome of incidence (events divided by number of eligible participants admitted to the hospital during the study period) of cardiac arrests without a pre‐existing NFR order, unplanned ICU admissions... · adult on acute hospital wards at risk of clinical deterioration
1 finding from 1 review