Nasal trauma (during assigned treatment) · preterm infants requiring primary respiratory support
Nasal high flow probably leads to lower nasal trauma (during assigned treatment) compared with continuous positive airway pressure (moderate certainty).
1 finding from 1 review
Mortality before hospital discharge · preterm infants requiring primary respiratory support
Nasal high flow showed no clear difference in death (before hospital discharge) compared with nasal intermittent positive pressure ventilation (low certainty).
1 finding from 1 review
Death · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
1 finding from 1 review
Treatment failure · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes treatment failure compared with continuous positive airway pressure (CPAP) (very low certainty).
1 finding from 1 review
Chronic lung disease · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
1 finding from 1 review
ICU length of stay (general intensive care patients) · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
1 finding from 1 review
Adverse events ‐ nasal trauma · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes adverse events ‐ nasal trauma compared with continuous positive airway pressure (CPAP) (very low certainty).
1 finding from 1 review
Adverse events ‐ abdominal overdistention · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))
It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes adverse events ‐ abdominal overdistention compared with continuous positive airway pressure (CPAP) (very low certainty).
1 finding from 1 review
Treatment failure (death or use of additional ventilatory support) · preterm infants with respiratory distress for initial respiratory support
It is very uncertain whether CPAP changes treatment failure (death or use of additional ventilatory support) compared with supplemental oxygen (very low certainty).
1 finding from 1 review
Duration of invasive ventilatory support · preterm infants < 37 weeks' gestational age requiring conventional mechanical ventilation for respiratory distress syndrome
1 finding from 1 review
Failed Treatment · preterm infants
It is very uncertain whether prophylactic or very early CPAP changes failed treatment defined as recurrent apnoea, hypoxia, hypercarbia… compared with supportive care (very low certainty).
1 finding from 1 review
Bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency at 36 weeks postmenstrual age · preterm infants
Prophylactic or very early CPAP showed no clear difference in bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency… compared with supportive care (moderate certainty).
1 finding from 1 review
Death at any time · preterm infants
Prophylactic or very early CPAP showed no clear difference in death at any time compared with supportive care (moderate certainty).
1 finding from 1 review
Death or oxygen requirement at 36 weeks' postmenstrual age · preterm infants
Prophylactic or very early CPAP showed no clear difference in combined outcome of death and bronchopulmonary dysplasia defined as… compared with supportive care (low certainty).
1 finding from 1 review
Pulmonary air leak defined as pneumothorax · preterm infants
Prophylactic or very early CPAP showed no clear difference in pulmonary air leak defined as pneumothorax compared with supportive care (low certainty).
1 finding from 1 review
Intraventricular haemorrhage, Papile grade 3/4 · preterm infants
Prophylactic or very early CPAP showed no clear difference in intraventricular haemorrhage grade 3 or 4 compared with supportive care (low certainty).
1 finding from 1 review
Neurodevelopmental disability · preterm infants
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found