Prophylactic or very early CPAP vs supportive care: Failed Treatment
It is very uncertain whether prophylactic or very early CPAP changes failed treatment defined as recurrent apnoea, hypoxia, hypercarbia… compared with supportive care (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Prophylactic or very early CPAP vs supportive care Failed treatment defined as recurrent apnoea, hypoxia, hypercarbia (such as PaCO₂ > 60 mmHg), increasing oxygen requirement, or the need for mechanical ventilation · preterm infants It is very uncertain whether prophylactic or very early CPAP changes failed treatment defined as recurrent apnoea, hypoxia, hypercarbia… compared with supportive care (very low certainty). Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants (2021) · Cochrane Headline outcomes only | RR 0.6 [0.49, 0.74] | 4 studies · 765 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.