Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

59 questions · 60 findings · 8 reviews

No studies found 9 · 15%GRADE not reported 2 · 3.3%Very low 10 · 16.7%Low 28 · 46.7%Moderate 9 · 15%High 2 · 3.3%

Oral ondansetron (weight based) vs placebo

Proportion of patients with cessation of vomiting · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration

Oral ondansetron (weight based) probably leads to higher proportion of patients with cessation of vomiting compared with placebo (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Ondansetron vs placebo

Risk for at least one adverse event per patient · patients with chronic kidney disease (CKD) pruritus

It is very uncertain whether summary of findings table ‐ Ondansetron changes risk for at least one adverse event per patient compared with placebo (very low certainty).

1 finding from 1 review