Change in burn‐related pruritus (VAS) ( · people with postburn pruritus
Ondansetron showed no clear difference in change in burn‐related pruritus (NAS) ( compared with diphenhydramine (antihistamine) (moderate certainty).
1 finding from 1 review
Adverse events · people with postburn pruritus
The review found no eligible studies for this question.
1 finding from 1 review
Pain · people with postburn pruritus
The review found no eligible studies for this question.
1 finding from 1 review
Maternal hypotension requiring intervention · women having spinal anaesthesia for caesarean section
Ondansetron may leads to lower maternal hypotension requiring intervention compared with control (low certainty).
1 finding from 1 review
Maternal hypertension requiring intervention · women having spinal anaesthesia for caesarean section
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Maternal bradycardia requiring intervention · women having spinal anaesthesia for caesarean section
Ondansetron may leads to lower maternal bradycardia requiring intervention compared with control (low certainty).
1 finding from 1 review
Maternal nausea and/or vomiting · women having spinal anaesthesia for caesarean section
Ondansetron may leads to lower maternal nausea and/or vomiting compared with control (low certainty).
1 finding from 1 review
Neonatal Apgar score < 8 at 5 minutes · women having spinal anaesthesia for caesarean section
1 finding from 1 review
Neonatal acidosis as defined by cord or neonatal blood with a pH < 7.2 · women having spinal anaesthesia for caesarean section
Ondansetron showed no clear difference in neonatal acidosis as defined by cord or neonatal blood with a pH < 7.2 compared with control (low certainty).
1 finding from 1 review
Neonatal unit admission · women having spinal anaesthesia for caesarean section
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of hospital stay · Pregnant women with hyperemesis gravidarum
It is very uncertain whether ondansetron changes days of hospital admission compared with promethazine (very low certainty).
1 finding from 1 review
Adverse effects: 1. Sedation · Pregnant women with hyperemesis gravidarum
Ondansetron may leads to lower intervention side effect: sedation compared with promethazine (low certainty).
1 finding from 1 review
Severity, reduction or cessation in nausea/vomiting 2. Number of episodes of emesis 3. Quality of life outcomes 4. Pregnancy complications 5. Adverse fetal/neonatal outcomes · Pregnant women with hyperemesis gravidarum
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Rate of admission during ED stay · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration
Oral ondansetron (weight based) probably leads to lower rate of admission during ED stay compared with placebo (moderate certainty).
1 finding from 1 review
Adverse events · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration
1 finding from 1 review
Rate of admission 72 hrs · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration
Oral ondansetron (weight based) showed no clear difference in rate of admission 72 hrs compared with placebo (low certainty).
2 findings from 1 review
Time to cessation of vomiting · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration
1 finding from 1 review
Rate of intravenous rehydration during ED stay · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration
Oral ondansetron (weight based) probably leads to lower rate of intravenous rehydration during ED stay compared with placebo (moderate certainty).
1 finding from 1 review
Rate of intravenous rehydration up to 72 hrs following discharge from ED (best ‐ worst scenario) · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration
Oral ondansetron (weight based) may leads to lower rate of intravenous rehydration up to 72 hrs following discharge… compared with placebo (low certainty).
1 finding from 1 review
Rate of intravenous rehydration up to 72 hrs following discharge from ED (worst ‐ best scenario) · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration
Oral ondansetron (weight based) may leads to lower rate of intravenous rehydration up to 72 hrs following discharge… compared with placebo (low certainty).
1 finding from 1 review