Question · asked by 1 review

Oral ondansetron (weight based) vs placebo: Rate of admission 72 hrs

Oral ondansetron (weight based) showed no clear difference in rate of admission 72 hrs compared with placebo (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Oral ondansetron (weight based) vs placebo
Rate of admission 72 hrs · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration
Oral ondansetron (weight based) showed no clear difference in rate of admission 72 hrs compared with placebo (low certainty).
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents (2011) · Cochrane Headline outcomes only
RR 0.6 [0.34, 1.04]3 studies · 461 participantsLow
Oral ondansetron (weight based) vs placebo
Rate of admission in 72 hrs · patients with vomiting related to acute gastroenteritis with mild to moderate dehydration
Oral ondansetron (weight based) showed no clear difference in rate of admission in 72 hrs compared with placebo (low certainty).
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents (2011) · Cochrane Headline outcomes only
RR 0.73 [0.43, 1.22]3 studies · 461 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents
2011 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.